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22 results

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Page 1
Homozygous Familial Hypercholesterolemia Patients With Identical Mutations Variably Express the LDLR (Low-Density Lipoprotein Receptor): Implications for the Efficacy of Evolocumab.
Thedrez A, Blom DJ, Ramin-Mangata S, Blanchard V, Croyal M, Chemello K, Nativel B, Pichelin M, Cariou B, Bourane S, Tang L, Farnier M, Raal FJ, Lambert G. Thedrez A, et al. Among authors: nativel b. Arterioscler Thromb Vasc Biol. 2018 Mar;38(3):592-598. doi: 10.1161/ATVBAHA.117.310217. Epub 2017 Dec 28. Arterioscler Thromb Vasc Biol. 2018. PMID: 29284604 Free PMC article. Clinical Trial.
PCSK9 inhibition with alirocumab reduces lipoprotein(a) levels in nonhuman primates by lowering apolipoprotein(a) production rate.
Croyal M, Tran TT, Blanchard RH, Le Bail JC, Villard EF, Poirier B, Aguesse A, Billon-Crossouard S, Ramin-Mangata S, Blanchard V, Nativel B, Chemello K, Khantalin I, Thedrez A, Janiak P, Krempf M, Boixel C, Lambert G, Guillot E. Croyal M, et al. Among authors: nativel b. Clin Sci (Lond). 2018 May 31;132(10):1075-1083. doi: 10.1042/CS20180040. Print 2018 May 31. Clin Sci (Lond). 2018. PMID: 29724769
PCSK9: from biology to clinical applications.
Blanchard V, Khantalin I, Ramin-Mangata S, Chémello K, Nativel B, Lambert G. Blanchard V, et al. Among authors: nativel b. Pathology. 2019 Feb;51(2):177-183. doi: 10.1016/j.pathol.2018.10.012. Epub 2018 Dec 4. Pathology. 2019. PMID: 30522786 Review.
Effects of proprotein convertase subtilisin kexin type 9 modulation in human pancreatic beta cells function.
Ramin-Mangata S, Thedrez A, Nativel B, Diotel N, Blanchard V, Wargny M, Aguesse A, Billon-Crossouard S, Vindis C, Le May C, Hulin P, Armanet M, Gmyr V, Pattou F, Croyal M, Meilhac O, Nobécourt E, Cariou B, Lambert G. Ramin-Mangata S, et al. Among authors: nativel b. Atherosclerosis. 2021 Jun;326:47-55. doi: 10.1016/j.atherosclerosis.2021.03.044. Epub 2021 Apr 20. Atherosclerosis. 2021. PMID: 33933263
Circulating PCSK9 levels are not associated with the conversion to type 2 diabetes.
Ramin-Mangata S, Wargny M, Pichelin M, Le May C, Thédrez A, Blanchard V, Nativel B, Santos RD, Benseñor IM, Lotufo PA, Lambert G, Cariou B. Ramin-Mangata S, et al. Among authors: nativel b. Atherosclerosis. 2020 Jan;293:49-56. doi: 10.1016/j.atherosclerosis.2019.11.027. Epub 2019 Nov 28. Atherosclerosis. 2020. PMID: 31835041
Kinetics of plasma apolipoprotein E isoforms by LC-MS/MS: a pilot study.
Blanchard V, Ramin-Mangata S, Billon-Crossouard S, Aguesse A, Durand M, Chemello K, Nativel B, Flet L, Chétiveaux M, Jacobi D, Bard JM, Ouguerram K, Lambert G, Krempf M, Croyal M. Blanchard V, et al. Among authors: nativel b. J Lipid Res. 2018 May;59(5):892-900. doi: 10.1194/jlr.P083576. Epub 2018 Mar 14. J Lipid Res. 2018. PMID: 29540575 Free PMC article.
A small molecule inhibitor of PCSK9 that antagonizes LDL receptor binding via interaction with a cryptic PCSK9 binding groove.
Evison BJ, Palmer JT, Lambert G, Treutlein H, Zeng J, Nativel B, Chemello K, Zhu Q, Wang J, Teng Y, Tang W, Xu Y, Rathi AK, Kumar S, Suchowerska AK, Parmar J, Dixon I, Kelly GE, Bonnar J. Evison BJ, et al. Among authors: nativel b. Bioorg Med Chem. 2020 Mar 15;28(6):115344. doi: 10.1016/j.bmc.2020.115344. Epub 2020 Jan 31. Bioorg Med Chem. 2020. PMID: 32051094 Free article.
22 results