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IFI16 is an innate immune sensor for intracellular DNA.
Unterholzner L, Keating SE, Baran M, Horan KA, Jensen SB, Sharma S, Sirois CM, Jin T, Latz E, Xiao TS, Fitzgerald KA, Paludan SR, Bowie AG. Unterholzner L, et al. Among authors: jin t. Nat Immunol. 2010 Nov;11(11):997-1004. doi: 10.1038/ni.1932. Epub 2010 Oct 3. Nat Immunol. 2010. PMID: 20890285 Free PMC article.
RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA.
Sirois CM, Jin T, Miller AL, Bertheloot D, Nakamura H, Horvath GL, Mian A, Jiang J, Schrum J, Bossaller L, Pelka K, Garbi N, Brewah Y, Tian J, Chang C, Chowdhury PS, Sims GP, Kolbeck R, Coyle AJ, Humbles AA, Xiao TS, Latz E. Sirois CM, et al. Among authors: jin t. J Exp Med. 2013 Oct 21;210(11):2447-63. doi: 10.1084/jem.20120201. Epub 2013 Sep 30. J Exp Med. 2013. PMID: 24081950 Free PMC article.
IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication.
Jakobsen MR, Bak RO, Andersen A, Berg RK, Jensen SB, Tengchuan J, Laustsen A, Hansen K, Ostergaard L, Fitzgerald KA, Xiao TS, Mikkelsen JG, Mogensen TH, Paludan SR. Jakobsen MR, et al. Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):E4571-80. doi: 10.1073/pnas.1311669110. Epub 2013 Oct 23. Proc Natl Acad Sci U S A. 2013. PMID: 24154727 Free PMC article.
3,551 results