Purwin TJ - Search Results

1

ERK-mediated phosphorylation regulates SOX10 sumoylation and targets expression in mutant BRAF melanoma.

Han S, Ren Y, He W, Liu H, Zhi Z, Zhu X, Yang T, Rong Y, Ma B, Purwin TJ, Ouyang Z, Li C, Wang X, Wang X, Yang H, Zheng Y, Aplin AE, Liu J, Shao Y. Han S, et al. Among authors: purwin tj. Nat Commun. 2018 Jan 2;9(1):28. doi: 10.1038/s41467-017-02354-x. Nat Commun. 2018. PMID: 29295999 Free PMC article.

2

Publisher Correction: ERK-mediated phosphorylation regulates SOX10 sumoylation and targets expression in mutant BRAF melanoma.

Han S, Ren Y, He W, Liu H, Zhi Z, Zhu X, Yang T, Rong Y, Ma B, Purwin TJ, Ouyang Z, Li C, Wang X, Wang X, Yang H, Zheng Y, Aplin AE, Liu J, Shao Y. Han S, et al. Among authors: purwin tj. Nat Commun. 2018 Apr 6;9(1):1404. doi: 10.1038/s41467-018-03710-1. Nat Commun. 2018. PMID: 29626208 Free PMC article.

3

Targeting SOX10-deficient cells to reduce the dormant-invasive phenotype state in melanoma.

Capparelli C, Purwin TJ, Glasheen M, Caksa S, Tiago M, Wilski N, Pomante D, Rosenbaum S, Nguyen MQ, Cai W, Franco-Barraza J, Zheng R, Kumar G, Chervoneva I, Shimada A, Rebecca VW, Snook AE, Hookim K, Xu X, Cukierman E, Herlyn M, Aplin AE. Capparelli C, et al. Among authors: purwin tj. Nat Commun. 2022 Mar 16;13(1):1381. doi: 10.1038/s41467-022-28801-y. Nat Commun. 2022. PMID: 35296667 Free PMC article.

4

RAC1 P29S regulates PD-L1 expression in melanoma.

Vu HL, Rosenbaum S, Purwin TJ, Davies MA, Aplin AE. Vu HL, et al. Among authors: purwin tj. Pigment Cell Melanoma Res. 2015 Sep;28(5):590-8. doi: 10.1111/pcmr.12392. Pigment Cell Melanoma Res. 2015. PMID: 26176707 Free PMC article.

5

MIG6 Is MEK Regulated and Affects EGF-Induced Migration in Mutant NRAS Melanoma.

Vu HL, Rosenbaum S, Capparelli C, Purwin TJ, Davies MA, Berger AC, Aplin AE. Vu HL, et al. Among authors: purwin tj. J Invest Dermatol. 2016 Feb;136(2):453-463. doi: 10.1016/j.jid.2015.11.012. Epub 2015 Nov 20. J Invest Dermatol. 2016. PMID: 26967478 Free PMC article.

6

Response and Resistance to Paradox-Breaking BRAF Inhibitor in Melanomas In Vivo and Ex Vivo.

Hartsough EJ, Kugel CH 3rd, Vido MJ, Berger AC, Purwin TJ, Goldberg A, Davies MA, Schiewer MJ, Knudsen KE, Bollag G, Aplin AE. Hartsough EJ, et al. Among authors: purwin tj. Mol Cancer Ther. 2018 Jan;17(1):84-95. doi: 10.1158/1535-7163.MCT-17-0705. Epub 2017 Nov 13. Mol Cancer Ther. 2018. PMID: 29133617 Free PMC article.

7

ErbB3 Targeting Enhances the Effects of MEK Inhibitor in Wild-Type BRAF/NRAS Melanoma.

Capparelli C, Purwin TJ, Heilman SA, Chervoneva I, McCue PA, Berger AC, Davies MA, Gershenwald JE, Krepler C, Aplin AE. Capparelli C, et al. Among authors: purwin tj. Cancer Res. 2018 Oct 1;78(19):5680-5693. doi: 10.1158/0008-5472.CAN-18-1001. Epub 2018 Aug 16. Cancer Res. 2018. PMID: 30115691 Free PMC article.

8

In Vivo ERK1/2 Reporter Predictively Models Response and Resistance to Combined BRAF and MEK Inhibitors in Melanoma.

Sanchez IM, Purwin TJ, Chervoneva I, Erkes DA, Nguyen MQ, Davies MA, Nathanson KL, Kemper K, Peeper DS, Aplin AE. Sanchez IM, et al. Among authors: purwin tj. Mol Cancer Ther. 2019 Sep;18(9):1637-1648. doi: 10.1158/1535-7163.MCT-18-1056. Epub 2019 Jul 3. Mol Cancer Ther. 2019. PMID: 31270153 Free PMC article.

9

Mutant BRAF and MEK Inhibitors Regulate the Tumor Immune Microenvironment via Pyroptosis.

Erkes DA, Cai W, Sanchez IM, Purwin TJ, Rogers C, Field CO, Berger AC, Hartsough EJ, Rodeck U, Alnemri ES, Aplin AE. Erkes DA, et al. Among authors: purwin tj. Cancer Discov. 2020 Feb;10(2):254-269. doi: 10.1158/2159-8290.CD-19-0672. Epub 2019 Dec 3. Cancer Discov. 2020. PMID: 31796433 Free PMC article.

10

A Genome-Wide Screen Identifies PDPK1 as a Target to Enhance the Efficacy of MEK1/2 Inhibitors in NRAS Mutant Melanoma.

Cai W, Nguyen MQ, Wilski NA, Purwin TJ, Vernon M, Tiago M, Aplin AE. Cai W, et al. Among authors: purwin tj. Cancer Res. 2022 Jul 18;82(14):2625-2639. doi: 10.1158/0008-5472.CAN-21-3217. Cancer Res. 2022. PMID: 35657206 Free PMC article.

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