Chernoff J - Search Results

1

Pak2 regulates myeloid-derived suppressor cell development in mice.

Zeng Y, Hahn S, Stokes J, Hoffman EA, Schmelz M, Proytcheva M, Chernoff J, Katsanis E. Zeng Y, et al. Among authors: chernoff j. Blood Adv. 2017 Oct 10;1(22):1923-1933. doi: 10.1182/bloodadvances.2017007435. eCollection 2017 Oct 10. Blood Adv. 2017. PMID: 29296839 Free PMC article.

2

Pak2 regulates hematopoietic progenitor cell proliferation, survival, and differentiation.

Zeng Y, Broxmeyer HE, Staser K, Chitteti BR, Park SJ, Hahn S, Cooper S, Sun Z, Jiang L, Yang X, Yuan J, Kosoff R, Sandusky G, Srour EF, Chernoff J, Clapp DW. Zeng Y, et al. Among authors: chernoff j. Stem Cells. 2015 May;33(5):1630-41. doi: 10.1002/stem.1951. Stem Cells. 2015. PMID: 25586960 Free PMC article.

3

Pak2 restrains endomitosis during megakaryopoiesis and alters cytoskeleton organization.

Kosoff RE, Aslan JE, Kostyak JC, Dulaimi E, Chow HY, Prudnikova TY, Radu M, Kunapuli SP, McCarty OJ, Chernoff J. Kosoff RE, et al. Among authors: chernoff j. Blood. 2015 May 7;125(19):2995-3005. doi: 10.1182/blood-2014-10-604504. Epub 2015 Mar 30. Blood. 2015. PMID: 25824689 Free PMC article.

4

PAK1 is a therapeutic target in acute myeloid leukemia and myelodysplastic syndrome.

Pandolfi A, Stanley RF, Yu Y, Bartholdy B, Pendurti G, Gritsman K, Boultwood J, Chernoff J, Verma A, Steidl U. Pandolfi A, et al. Among authors: chernoff j. Blood. 2015 Aug 27;126(9):1118-27. doi: 10.1182/blood-2014-12-618801. Epub 2015 Jul 13. Blood. 2015. PMID: 26170031 Free PMC article.

5

p21-activated kinase 2 regulates HSPC cytoskeleton, migration, and homing via CDC42 activation and interaction with β-Pix.

Reddy PN, Radu M, Xu K, Wood J, Harris CE, Chernoff J, Williams DA. Reddy PN, et al. Among authors: chernoff j. Blood. 2016 Apr 21;127(16):1967-75. doi: 10.1182/blood-2016-01-693572. Epub 2016 Mar 1. Blood. 2016. PMID: 26932803 Free PMC article.

6

p21-activated kinase regulates mast cell degranulation via effects on calcium mobilization and cytoskeletal dynamics.

Allen JD, Jaffer ZM, Park SJ, Burgin S, Hofmann C, Sells MA, Chen S, Derr-Yellin E, Michels EG, McDaniel A, Bessler WK, Ingram DA, Atkinson SJ, Travers JB, Chernoff J, Clapp DW. Allen JD, et al. Among authors: chernoff j. Blood. 2009 Mar 19;113(12):2695-705. doi: 10.1182/blood-2008-06-160861. Epub 2009 Jan 5. Blood. 2009. PMID: 19124833 Free PMC article.

7

Pak2 kinase restrains mast cell FcεRI receptor signaling through modulation of Rho protein guanine nucleotide exchange factor (GEF) activity.

Kosoff R, Chow HY, Radu M, Chernoff J. Kosoff R, et al. Among authors: chernoff j. J Biol Chem. 2013 Jan 11;288(2):974-83. doi: 10.1074/jbc.M112.422295. Epub 2012 Nov 30. J Biol Chem. 2013. PMID: 23204526 Free PMC article.

8

The Rac GTPase effector p21-activated kinase is essential for hematopoietic stem/progenitor cell migration and engraftment.

Dorrance AM, De Vita S, Radu M, Reddy PN, McGuinness MK, Harris CE, Mathieu R, Lane SW, Kosoff R, Milsom MD, Chernoff J, Williams DA. Dorrance AM, et al. Among authors: chernoff j. Blood. 2013 Mar 28;121(13):2474-82. doi: 10.1182/blood-2012-10-460709. Epub 2013 Jan 18. Blood. 2013. PMID: 23335370 Free PMC article.

9

Pak2 is required for actin cytoskeleton remodeling, TCR signaling, and normal thymocyte development and maturation.

Phee H, Au-Yeung BB, Pryshchep O, O'Hagan KL, Fairbairn SG, Radu M, Kosoff R, Mollenauer M, Cheng D, Chernoff J, Weiss A. Phee H, et al. Among authors: chernoff j. Elife. 2014 May 13;3:e02270. doi: 10.7554/eLife.02270. Elife. 2014. PMID: 24843022 Free PMC article.

10

Gq-mediated Akt translocation to the membrane: a novel PIP3-independent mechanism in platelets.

Badolia R, Manne BK, Dangelmaier C, Chernoff J, Kunapuli SP. Badolia R, et al. Among authors: chernoff j. Blood. 2015 Jan 1;125(1):175-84. doi: 10.1182/blood-2014-05-576306. Epub 2014 Oct 20. Blood. 2015. PMID: 25331114 Free PMC article.

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