Adler AJ - Search Results

1

An Immunotherapeutic CD137 Agonist Releases Eomesodermin from ThPOK Repression in CD4 T Cells.

Mittal P, Abblett R, Ryan JM, Hagymasi AT, Agyekum-Yamoah A, Svedova J, Reiner SL, St Rose MC, Hanley MP, Vella AT, Adler AJ. Mittal P, et al. Among authors: adler aj. J Immunol. 2018 Feb 15;200(4):1513-1526. doi: 10.4049/jimmunol.1701039. Epub 2018 Jan 5. J Immunol. 2018. PMID: 29305435 Free PMC article.

2

In vivo CD4+ T cell tolerance induction versus priming is independent of the rate and number of cell divisions.

Adler AJ, Huang CT, Yochum GS, Marsh DW, Pardoll DM. Adler AJ, et al. J Immunol. 2000 Jan 15;164(2):649-55. doi: 10.4049/jimmunol.164.2.649. J Immunol. 2000. PMID: 10623806

3

CD4 cell priming and tolerization are differentially programmed by APCs upon initial engagement.

Higgins AD, Mihalyo MA, McGary PW, Adler AJ. Higgins AD, et al. Among authors: adler aj. J Immunol. 2002 Jun 1;168(11):5573-81. doi: 10.4049/jimmunol.168.11.5573. J Immunol. 2002. PMID: 12023353

4

Effector CD4 cells are tolerized upon exposure to parenchymal self-antigen.

Higgins AD, Mihalyo MA, Adler AJ. Higgins AD, et al. Among authors: adler aj. J Immunol. 2002 Oct 1;169(7):3622-9. doi: 10.4049/jimmunol.169.7.3622. J Immunol. 2002. PMID: 12244153 Free PMC article.

5

Effector CD4 cell tolerization is mediated through functional inactivation and involves preferential impairment of TNF-alpha and IFN-gamma expression potentials.

Long M, Higgins AD, Mihalyo MA, Adler AJ. Long M, et al. Among authors: adler aj. Cell Immunol. 2003 Aug;224(2):114-21. doi: 10.1016/j.cellimm.2003.08.008. Cell Immunol. 2003. PMID: 14609577 Free PMC article.

6

In vivo cyclophosphamide and IL-2 treatment impedes self-antigen-induced effector CD4 cell tolerization: implications for adoptive immunotherapy.

Mihalyo MA, Doody AD, McAleer JP, Nowak EC, Long M, Yang Y, Adler AJ. Mihalyo MA, et al. Among authors: adler aj. J Immunol. 2004 May 1;172(9):5338-45. doi: 10.4049/jimmunol.172.9.5338. J Immunol. 2004. PMID: 15100273 Free PMC article.

7

Glycoprotein 96 can chaperone both MHC class I- and class II-restricted epitopes for in vivo presentation, but selectively primes CD8+ T cell effector function.

Doody AD, Kovalchin JT, Mihalyo MA, Hagymasi AT, Drake CG, Adler AJ. Doody AD, et al. Among authors: adler aj. J Immunol. 2004 May 15;172(10):6087-92. doi: 10.4049/jimmunol.172.10.6087. J Immunol. 2004. PMID: 15128793 Free PMC article.

8

T-bet down-modulation in tolerized Th1 effector CD4 cells confers a TCR-distal signaling defect that selectively impairs IFN-gamma expression.

Long M, Slaiby AM, Hagymasi AT, Mihalyo MA, Lichtler AC, Reiner SL, Adler AJ. Long M, et al. Among authors: adler aj. J Immunol. 2006 Jan 15;176(2):1036-45. doi: 10.4049/jimmunol.176.2.1036. J Immunol. 2006. PMID: 16393991 Free PMC article.

9

Cutting edge: Paracrine, but not autocrine, IL-2 signaling is sustained during early antiviral CD4 T cell response.

Long M, Adler AJ. Long M, et al. Among authors: adler aj. J Immunol. 2006 Oct 1;177(7):4257-61. doi: 10.4049/jimmunol.177.7.4257. J Immunol. 2006. PMID: 16982857 Free PMC article.

10

Dendritic cells program non-immunogenic prostate-specific T cell responses beginning at early stages of prostate tumorigenesis.

Mihalyo MA, Hagymasi AT, Slaiby AM, Nevius EE, Adler AJ. Mihalyo MA, et al. Among authors: adler aj. Prostate. 2007 Apr 1;67(5):536-46. doi: 10.1002/pros.20549. Prostate. 2007. PMID: 17221844 Free PMC article.

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