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Study of an extended family with CTLA-4 deficiency suggests a CD28/CTLA-4 independent mechanism responsible for differences in disease manifestations and severity.
Hou TZ, Olbrich P, Soto JML, Sanchez B, Moreno PS, Borte S, Stauss HJ, Burns SO, Walker LSK, Pan-Hammarström Q, Hammarström L, Sansom DM, Neth O. Hou TZ, et al. Among authors: sansom dm. Clin Immunol. 2018 Mar;188:94-102. doi: 10.1016/j.clim.2018.01.001. Epub 2018 Jan 3. Clin Immunol. 2018. PMID: 29305966 Free article.
CTLA4 gene polymorphism and autoimmunity.
Gough SC, Walker LS, Sansom DM. Gough SC, et al. Among authors: sansom dm. Immunol Rev. 2005 Apr;204:102-15. doi: 10.1111/j.0105-2896.2005.00249.x. Immunol Rev. 2005. PMID: 15790353 Review.
116 results