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The EndoC-βH1 cell line is a valid model of human beta cells and applicable for screenings to identify novel drug target candidates.
Tsonkova VG, Sand FW, Wolf XA, Grunnet LG, Kirstine Ringgaard A, Ingvorsen C, Winkel L, Kalisz M, Dalgaard K, Bruun C, Fels JJ, Helgstrand C, Hastrup S, Öberg FK, Vernet E, Sandrini MPB, Shaw AC, Jessen C, Grønborg M, Hald J, Willenbrock H, Madsen D, Wernersson R, Hansson L, Jensen JN, Plesner A, Alanentalo T, Petersen MBK, Grapin-Botton A, Honoré C, Ahnfelt-Rønne J, Hecksher-Sørensen J, Ravassard P, Madsen OD, Rescan C, Frogne T. Tsonkova VG, et al. Among authors: winkel l. Mol Metab. 2018 Feb;8:144-157. doi: 10.1016/j.molmet.2017.12.007. Epub 2017 Dec 19. Mol Metab. 2018. PMID: 29307512 Free PMC article.
Oxygen releasing hydrogels for beta cell assisted therapy.
Toftdal MS, Taebnia N, Kadumudi FB, Andresen TL, Frogne T, Winkel L, Grunnet LG, Dolatshahi-Pirouz A. Toftdal MS, et al. Among authors: winkel l. Int J Pharm. 2021 Jun 1;602:120595. doi: 10.1016/j.ijpharm.2021.120595. Epub 2021 Apr 20. Int J Pharm. 2021. PMID: 33892060 Free article.
Designing a retrievable and scalable cell encapsulation device for potential treatment of type 1 diabetes.
An D, Chiu A, Flanders JA, Song W, Shou D, Lu YC, Grunnet LG, Winkel L, Ingvorsen C, Christophersen NS, Fels JJ, Sand FW, Ji Y, Qi L, Pardo Y, Luo D, Silberstein M, Fan J, Ma M. An D, et al. Among authors: winkel l. Proc Natl Acad Sci U S A. 2018 Jan 9;115(2):E263-E272. doi: 10.1073/pnas.1708806115. Epub 2017 Dec 26. Proc Natl Acad Sci U S A. 2018. PMID: 29279393 Free PMC article.
A Safe, Fibrosis-Mitigating, and Scalable Encapsulation Device Supports Long-Term Function of Insulin-Producing Cells.
Liu W, Flanders JA, Wang LH, Liu Q, Bowers DT, Wang K, Chiu A, Wang X, Ernst AU, Shariati K, Caserto JS, Parker B, Gao D, Plesser MD, Grunnet LG, Rescan C, Pimentel Carletto R, Winkel L, Melero-Martin JM, Ma M. Liu W, et al. Among authors: winkel l. Small. 2022 Feb;18(8):e2104899. doi: 10.1002/smll.202104899. Epub 2021 Dec 13. Small. 2022. PMID: 34897997 Free PMC article.
Long-term viability through selective permeability.
Coppieters K, Winkel L, von Herrath M. Coppieters K, et al. Among authors: winkel l. Nat Biomed Eng. 2020 Aug;4(8):763-764. doi: 10.1038/s41551-020-0602-1. Nat Biomed Eng. 2020. PMID: 32778784 No abstract available.
91 results