Orr A - Search Results

1

Distinct temporal roles for the promyelocytic leukaemia (PML) protein in the sequential regulation of intracellular host immunity to HSV-1 infection.

Alandijany T, Roberts APE, Conn KL, Loney C, McFarlane S, Orr A, Boutell C. Alandijany T, et al. Among authors: orr a. PLoS Pathog. 2018 Jan 8;14(1):e1006769. doi: 10.1371/journal.ppat.1006769. eCollection 2018 Jan. PLoS Pathog. 2018. PMID: 29309427 Free PMC article.

2

A viral ubiquitin ligase has substrate preferential SUMO targeted ubiquitin ligase activity that counteracts intrinsic antiviral defence.

Boutell C, Cuchet-Lourenço D, Vanni E, Orr A, Glass M, McFarlane S, Everett RD. Boutell C, et al. Among authors: orr a. PLoS Pathog. 2011 Sep;7(9):e1002245. doi: 10.1371/journal.ppat.1002245. Epub 2011 Sep 15. PLoS Pathog. 2011. PMID: 21949651 Free PMC article.

3

The histone chaperone HIRA promotes the induction of host innate immune defences in response to HSV-1 infection.

McFarlane S, Orr A, Roberts APE, Conn KL, Iliev V, Loney C, da Silva Filipe A, Smollett K, Gu Q, Robertson N, Adams PD, Rai TS, Boutell C. McFarlane S, et al. Among authors: orr a. PLoS Pathog. 2019 Mar 22;15(3):e1007667. doi: 10.1371/journal.ppat.1007667. eCollection 2019 Mar. PLoS Pathog. 2019. PMID: 30901352 Free PMC article.

4

PML residue lysine 160 is required for the degradation of PML induced by herpes simplex virus type 1 regulatory protein ICP0.

Boutell C, Orr A, Everett RD. Boutell C, et al. Among authors: orr a. J Virol. 2003 Aug;77(16):8686-94. doi: 10.1128/jvi.77.16.8686-8694.2003. J Virol. 2003. PMID: 12885887 Free PMC article.

5

Phenotype of a herpes simplex virus type 1 mutant that fails to express immediate-early regulatory protein ICP0.

Everett RD, Boutell C, Orr A. Everett RD, et al. Among authors: orr a. J Virol. 2004 Feb;78(4):1763-74. doi: 10.1128/jvi.78.4.1763-1774.2004. J Virol. 2004. PMID: 14747541 Free PMC article.

6

Reciprocal activities between herpes simplex virus type 1 regulatory protein ICP0, a ubiquitin E3 ligase, and ubiquitin-specific protease USP7.

Boutell C, Canning M, Orr A, Everett RD. Boutell C, et al. Among authors: orr a. J Virol. 2005 Oct;79(19):12342-54. doi: 10.1128/JVI.79.19.12342-12354.2005. J Virol. 2005. PMID: 16160161 Free PMC article.

7

Herpes simplex virus type 1 ICP0 phosphorylation mutants impair the E3 ubiquitin ligase activity of ICP0 in a cell type-dependent manner.

Boutell C, Everett R, Hilliard J, Schaffer P, Orr A, Davido D. Boutell C, et al. Among authors: orr a. J Virol. 2008 Nov;82(21):10647-56. doi: 10.1128/JVI.01063-08. Epub 2008 Aug 20. J Virol. 2008. PMID: 18715910 Free PMC article.

8

Comparison of the biological and biochemical activities of several members of the alphaherpesvirus ICP0 family of proteins.

Everett RD, Boutell C, McNair C, Grant L, Orr A. Everett RD, et al. Among authors: orr a. J Virol. 2010 Apr;84(7):3476-87. doi: 10.1128/JVI.02544-09. Epub 2010 Jan 27. J Virol. 2010. PMID: 20106921 Free PMC article.

9

SUMO pathway dependent recruitment of cellular repressors to herpes simplex virus type 1 genomes.

Cuchet-Lourenço D, Boutell C, Lukashchuk V, Grant K, Sykes A, Murray J, Orr A, Everett RD. Cuchet-Lourenço D, et al. Among authors: orr a. PLoS Pathog. 2011 Jul;7(7):e1002123. doi: 10.1371/journal.ppat.1002123. Epub 2011 Jul 14. PLoS Pathog. 2011. PMID: 21779164 Free PMC article.

10

Everett RD, Boutell C, Pheasant K, Cuchet-Lourenço D, Orr A. Everett RD, et al. Among authors: orr a. J Virol. 2014 Mar;88(5):2763-74. doi: 10.1128/JVI.03417-13. Epub 2013 Dec 18. J Virol. 2014. PMID: 24352468 Free PMC article.

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