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Identification of novel and potent inhibitors of SARS-CoV-2 main protease from DNA-encoded chemical libraries.
Akaberi D, Pourghasemi Lati M, Krambrich J, Berger J, Neilsen G, Strandback E, Turunen SP, Wannberg J, Gullberg H, Moche M, Chinthakindi PK, Nyman T, Sarafianos SG, Sandström A, Järhult JD, Sandberg K, Lundkvist Å, Verho O, Lennerstrand J. Akaberi D, et al. Among authors: nyman t. Antimicrob Agents Chemother. 2024 Oct 8;68(10):e0090924. doi: 10.1128/aac.00909-24. Epub 2024 Aug 28. Antimicrob Agents Chemother. 2024. PMID: 39194208 Free PMC article.
In situ proteolysis for protein crystallization and structure determination.
Dong A, Xu X, Edwards AM; Midwest Center for Structural Genomics; Structural Genomics Consortium; Chang C, Chruszcz M, Cuff M, Cymborowski M, Di Leo R, Egorova O, Evdokimova E, Filippova E, Gu J, Guthrie J, Ignatchenko A, Joachimiak A, Klostermann N, Kim Y, Korniyenko Y, Minor W, Que Q, Savchenko A, Skarina T, Tan K, Yakunin A, Yee A, Yim V, Zhang R, Zheng H, Akutsu M, Arrowsmith C, Avvakumov GV, Bochkarev A, Dahlgren LG, Dhe-Paganon S, Dimov S, Dombrovski L, Finerty P Jr, Flodin S, Flores A, Gräslund S, Hammerström M, Herman MD, Hong BS, Hui R, Johansson I, Liu Y, Nilsson M, Nedyalkova L, Nordlund P, Nyman T, Min J, Ouyang H, Park HW, Qi C, Rabeh W, Shen L, Shen Y, Sukumard D, Tempel W, Tong Y, Tresagues L, Vedadi M, Walker JR, Weigelt J, Welin M, Wu H, Xiao T, Zeng H, Zhu H. Dong A, et al. Among authors: nyman t. Nat Methods. 2007 Dec;4(12):1019-21. doi: 10.1038/nmeth1118. Epub 2007 Nov 4. Nat Methods. 2007. PMID: 17982461 Free PMC article.
359 results