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Decision-making in early clinical drug development.
Frewer P, Mitchell P, Watkins C, Matcham J. Frewer P, et al. Among authors: matcham j. Pharm Stat. 2016 May;15(3):255-63. doi: 10.1002/pst.1746. Epub 2016 Mar 17. Pharm Stat. 2016. PMID: 26991401
Impact of a five-dimensional framework on R&D productivity at AstraZeneca.
Morgan P, Brown DG, Lennard S, Anderton MJ, Barrett JC, Eriksson U, Fidock M, Hamrén B, Johnson A, March RE, Matcham J, Mettetal J, Nicholls DJ, Platz S, Rees S, Snowden MA, Pangalos MN. Morgan P, et al. Among authors: matcham j. Nat Rev Drug Discov. 2018 Mar;17(3):167-181. doi: 10.1038/nrd.2017.244. Epub 2018 Jan 19. Nat Rev Drug Discov. 2018. PMID: 29348681
A statistician's perspective on biomarkers in drug development.
Jenkins M, Flynn A, Smart T, Harbron C, Sabin T, Ratnayake J, Delmar P, Herath A, Jarvis P, Matcham J; PSI Biomarker Special Interest Group. Jenkins M, et al. Among authors: matcham j. Pharm Stat. 2011 Nov-Dec;10(6):494-507. doi: 10.1002/pst.532. Epub 2011 Dec 8. Pharm Stat. 2011. PMID: 22162336 Review.
Embracing model-based designs for dose-finding trials.
Love SB, Brown S, Weir CJ, Harbron C, Yap C, Gaschler-Markefski B, Matcham J, Caffrey L, McKevitt C, Clive S, Craddock C, Spicer J, Cornelius V. Love SB, et al. Among authors: matcham j. Br J Cancer. 2017 Jul 25;117(3):332-339. doi: 10.1038/bjc.2017.186. Epub 2017 Jun 29. Br J Cancer. 2017. PMID: 28664918 Free PMC article. Review.
Missing data: discussion points from the PSI missing data expert group.
Burzykowski T, Carpenter J, Coens C, Evans D, France L, Kenward M, Lane P, Matcham J, Morgan D, Phillips A, Roger J, Sullivan B, White I, Yu LM; of the PSI Missing Data Expert Group. Burzykowski T, et al. Among authors: matcham j. Pharm Stat. 2010 Oct-Dec;9(4):288-97. doi: 10.1002/pst.391. Pharm Stat. 2010. PMID: 19844946
A Quantitative Process for Enhancing End of Phase 2 Decisions.
Sabin T, Matcham J, Bray S, Copas A, Parmar MK. Sabin T, et al. Among authors: matcham j. Stat Biopharm Res. 2014 Jan;6(1):67-77. doi: 10.1080/19466315.2013.852617. Epub 2014 Feb 1. Stat Biopharm Res. 2014. PMID: 24683441 Free PMC article.
38 results