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Biochemical characterisation of a Kunitz-type inhibitor from Tamarindus indica L. seeds and its efficacy in reducing plasma leptin in an experimental model of obesity.
Medeiros AF, Costa IS, Carvalho FMC, Kiyota S, Souza BBP, Sifuentes DN, Serquiz RP, Maciel BLL, Uchôa AF, Santos EAD, Morais AHA. Medeiros AF, et al. Among authors: santos ead. J Enzyme Inhib Med Chem. 2018 Dec;33(1):334-348. doi: 10.1080/14756366.2017.1419220. J Enzyme Inhib Med Chem. 2018. PMID: 29322840 Free PMC article.
Structural insights and molecular dynamics into the inhibitory mechanism of a Kunitz-type trypsin inhibitor from Tamarindus indica L.
de Medeiros AF, de Souza BBP, Coutinho LP, Murad AM, Dos Santos PIM, Monteiro NKV, Santos EAD, Maciel BLL, de Araújo Morais AH. de Medeiros AF, et al. Among authors: santos ead. J Enzyme Inhib Med Chem. 2021 Dec;36(1):480-490. doi: 10.1080/14756366.2021.1876686. J Enzyme Inhib Med Chem. 2021. PMID: 33491503 Free PMC article.
Supplementation with a new trypsin inhibitor from peanut is associated with reduced fasting glucose, weight control, and increased plasma CCK secretion in an animal model.
Serquiz AC, Machado RJ, Serquiz RP, Lima VC, de Carvalho FM, Carneiro MA, Maciel BL, Uchôa AF, Santos EA, Morais AH. Serquiz AC, et al. J Enzyme Inhib Med Chem. 2016 Dec;31(6):1261-9. doi: 10.3109/14756366.2015.1103236. Epub 2016 Feb 29. J Enzyme Inhib Med Chem. 2016. PMID: 26928305 Free article.
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