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Page 1
Development of a Scalable, Chromatography-Free Synthesis of t-Bu-SMS-Phos and Application to the Synthesis of an Important Chiral CF3-Alcohol Derivative with High Enantioselectivity Using Rh-Catalyzed Asymmetric Hydrogenation.
Sieber JD, Rodriguez S, Frutos R, Buono F, Zhang Y, Li N, Qu B, Premasiri A, Li Z, Han ZS, Xu Y, Byrne D, Haddad N, Lorenz J, Grinberg N, Kurouski D, Lee H, Narayanan B, Nummy L, Mulder J, Brown JD, Granger A, Gao J, Krawiec M, Williams Z, Pennino S, Song JJ, Hossain A, Yee NK, Busacca C, Roschangar F, Xin Y, Mao Z, Zhang X, Hong Y, Senanayake CH. Sieber JD, et al. Among authors: buono f. J Org Chem. 2018 Feb 2;83(3):1448-1461. doi: 10.1021/acs.joc.7b03022. Epub 2018 Jan 23. J Org Chem. 2018. PMID: 29323903
Addressing the configuration stability of lithiated secondary benzylic carbamates for the development of a noncryogenic stereospecific boronate rearrangement.
Fandrick KR, Patel ND, Mulder JA, Gao J, Konrad M, Archer E, Buono FG, Duran A, Schmid R, Daeubler J, Fandrick DR, Ma S, Grinberg N, Lee H, Busacca CA, Song JJ, Yee NK, Senanayake CH. Fandrick KR, et al. Org Lett. 2014 Sep 5;16(17):4360-3. doi: 10.1021/ol502060c. Epub 2014 Aug 25. Org Lett. 2014. PMID: 25153850
Development of an asymmetric synthesis of a chiral quaternary FLAP inhibitor.
Fandrick KR, Mulder JA, Patel ND, Gao J, Konrad M, Archer E, Buono FG, Duran A, Schmid R, Daeubler J, Desrosiers JN, Zeng X, Rodriguez S, Ma S, Qu B, Li Z, Fandrick DR, Grinberg N, Lee H, Bosanac T, Takahashi H, Chen Z, Bartolozzi A, Nemoto P, Busacca CA, Song JJ, Yee NK, Mahaney PE, Senanayake CH. Fandrick KR, et al. J Org Chem. 2015 Feb 6;80(3):1651-60. doi: 10.1021/jo502550h. Epub 2015 Jan 22. J Org Chem. 2015. PMID: 25562342
Sequential C-H Arylation and Enantioselective Hydrogenation Enables Ideal Asymmetric Entry to the Indenopiperidine Core of an 11β-HSD-1 Inhibitor.
Wei X, Qu B, Zeng X, Savoie J, Fandrick KR, Desrosiers JN, Tcyrulnikov S, Marsini MA, Buono FG, Li Z, Yang BS, Tang W, Haddad N, Gutierrez O, Wang J, Lee H, Ma S, Campbell S, Lorenz JC, Eckhardt M, Himmelsbach F, Peters S, Patel ND, Tan Z, Yee NK, Song JJ, Roschangar F, Kozlowski MC, Senanayake CH. Wei X, et al. Among authors: buono fg. J Am Chem Soc. 2016 Nov 30;138(47):15473-15481. doi: 10.1021/jacs.6b09764. Epub 2016 Nov 17. J Am Chem Soc. 2016. PMID: 27794616 Free PMC article.
Carbamoyl Anion Addition to Azirines.
Kerner MJ, Kuttruff CA, Chevliakov M, Buono FG, Gao DA, Krawiec M, Busacca CA, Senanayake CH, Wipf P, Reeves JT. Kerner MJ, et al. Org Lett. 2021 Jun 4;23(11):4396-4399. doi: 10.1021/acs.orglett.1c01334. Epub 2021 May 14. Org Lett. 2021. PMID: 33988373
Novel 1,4-homofragmentation via an alpha-lactone.
Godfrey JD Jr, Fox RT, Buono FG, Gougoutas JZ, Malley MF. Godfrey JD Jr, et al. Among authors: buono fg. J Org Chem. 2006 Oct 27;71(22):8647-50. doi: 10.1021/jo0613380. J Org Chem. 2006. PMID: 17064050
135 results