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A New Secretory Peptide of Natriuretic Peptide Family, Osteocrin, Suppresses the Progression of Congestive Heart Failure After Myocardial Infarction.
Miyazaki T, Otani K, Chiba A, Nishimura H, Tokudome T, Takano-Watanabe H, Matsuo A, Ishikawa H, Shimamoto K, Fukui H, Kanai Y, Yasoda A, Ogata S, Nishimura K, Minamino N, Mochizuki N. Miyazaki T, et al. Among authors: kanai y. Circ Res. 2018 Mar 2;122(5):742-751. doi: 10.1161/CIRCRESAHA.117.312624. Epub 2018 Jan 11. Circ Res. 2018. PMID: 29326144
Circulating osteocrin stimulates bone growth by limiting C-type natriuretic peptide clearance.
Kanai Y, Yasoda A, Mori KP, Watanabe-Takano H, Nagai-Okatani C, Yamashita Y, Hirota K, Ueda Y, Yamauchi I, Kondo E, Yamanaka S, Sakane Y, Nakao K, Fujii T, Yokoi H, Minamino N, Mukoyama M, Mochizuki N, Inagaki N. Kanai Y, et al. J Clin Invest. 2017 Nov 1;127(11):4136-4147. doi: 10.1172/JCI94912. Epub 2017 Oct 9. J Clin Invest. 2017. PMID: 28990933 Free PMC article.
Mechanical load regulates bone growth via periosteal Osteocrin.
Watanabe-Takano H, Ochi H, Chiba A, Matsuo A, Kanai Y, Fukuhara S, Ito N, Sako K, Miyazaki T, Tainaka K, Harada I, Sato S, Sawada Y, Minamino N, Takeda S, Ueda HR, Yasoda A, Mochizuki N. Watanabe-Takano H, et al. Among authors: kanai y. Cell Rep. 2021 Jul 13;36(2):109380. doi: 10.1016/j.celrep.2021.109380. Cell Rep. 2021. PMID: 34260913 Free article.
Osteocrin, a bone-derived humoral factor, exerts a renoprotective role in ischemia-reperfusion injury in mice.
Nishiguchi Y, Hata Y, Date R, Fujimoto D, Umemoto S, Kanki T, Yokoi H, Mori KP, Handa T, Watanabe-Takano H, Kanai Y, Yasoda A, Izumi Y, Kakizoe Y, Mochizuki N, Mukoyama M, Kuwabara T. Nishiguchi Y, et al. Among authors: kanai y. Nephrol Dial Transplant. 2022 Feb 25;37(3):444-453. doi: 10.1093/ndt/gfab286. Nephrol Dial Transplant. 2022. PMID: 34610136 Free PMC article.
Exogenous C-type natriuretic peptide restores normal growth and prevents early growth plate closure in its deficient rats.
Hirota K, Furuya M, Morozumi N, Yoshikiyo K, Yotsumoto T, Jindo T, Nakamura R, Murakami K, Ueda Y, Hanada T, Sade H, Yoshida S, Enomoto K, Kanai Y, Yamauchi I, Yamashita T, Ueda-Sakane Y, Fujii T, Yasoda A, Inagaki N. Hirota K, et al. Among authors: kanai y. PLoS One. 2018 Sep 20;13(9):e0204172. doi: 10.1371/journal.pone.0204172. eCollection 2018. PLoS One. 2018. PMID: 30235256 Free PMC article.
Circulatory CNP Rescues Craniofacial Hypoplasia in Achondroplasia.
Yamanaka S, Nakao K, Koyama N, Isobe Y, Ueda Y, Kanai Y, Kondo E, Fujii T, Miura M, Yasoda A, Nakao K, Bessho K. Yamanaka S, et al. Among authors: kanai y. J Dent Res. 2017 Dec;96(13):1526-1534. doi: 10.1177/0022034517716437. Epub 2017 Jun 23. J Dent Res. 2017. PMID: 28644737
1,503 results