Kampmann M - Search Results

1

Dual gene activation and knockout screen reveals directional dependencies in genetic networks.

Boettcher M, Tian R, Blau JA, Markegard E, Wagner RT, Wu D, Mo X, Biton A, Zaitlen N, Fu H, McCormick F, Kampmann M, McManus MT. Boettcher M, et al. Among authors: kampmann m. Nat Biotechnol. 2018 Feb;36(2):170-178. doi: 10.1038/nbt.4062. Epub 2018 Jan 15. Nat Biotechnol. 2018. PMID: 29334369 Free PMC article.

2

Pharmacologic activation of a compensatory integrated stress response kinase promotes mitochondrial remodeling in PERK-deficient cells.

Perea V, Baron KR, Dolina V, Aviles G, Kim G, Rosarda JD, Guo X, Kampmann M, Wiseman RL. Perea V, et al. Among authors: kampmann m. Cell Chem Biol. 2023 Dec 21;30(12):1571-1584.e5. doi: 10.1016/j.chembiol.2023.10.006. Epub 2023 Nov 2. Cell Chem Biol. 2023. PMID: 37922906 Free PMC article.

3

A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility.

Bassik MC, Kampmann M, Lebbink RJ, Wang S, Hein MY, Poser I, Weibezahn J, Horlbeck MA, Chen S, Mann M, Hyman AA, Leproust EM, McManus MT, Weissman JS. Bassik MC, et al. Among authors: kampmann m. Cell. 2013 Feb 14;152(4):909-22. doi: 10.1016/j.cell.2013.01.030. Epub 2013 Feb 8. Cell. 2013. PMID: 23394947 Free PMC article.

4

Functional genomics platform for pooled screening and generation of mammalian genetic interaction maps.

Kampmann M, Bassik MC, Weissman JS. Kampmann M, et al. Nat Protoc. 2014 Aug;9(8):1825-47. doi: 10.1038/nprot.2014.103. Epub 2014 Jul 3. Nat Protoc. 2014. PMID: 24992097 Free PMC article.

5

CRISPRi and CRISPRa Screens in Mammalian Cells for Precision Biology and Medicine.

Kampmann M. Kampmann M. ACS Chem Biol. 2018 Feb 16;13(2):406-416. doi: 10.1021/acschembio.7b00657. Epub 2017 Oct 24. ACS Chem Biol. 2018. PMID: 29035510 Free PMC article. Review.

6

Mapping the Genetic Landscape of Human Cells.

Horlbeck MA, Xu A, Wang M, Bennett NK, Park CY, Bogdanoff D, Adamson B, Chow ED, Kampmann M, Peterson TR, Nakamura K, Fischbach MA, Weissman JS, Gilbert LA. Horlbeck MA, et al. Among authors: kampmann m. Cell. 2018 Aug 9;174(4):953-967.e22. doi: 10.1016/j.cell.2018.06.010. Epub 2018 Jul 19. Cell. 2018. PMID: 30033366 Free PMC article.

7

Ceapins block the unfolded protein response sensor ATF6α by inducing a neomorphic inter-organelle tether.

Torres SE, Gallagher CM, Plate L, Gupta M, Liem CR, Guo X, Tian R, Stroud RM, Kampmann M, Weissman JS, Walter P. Torres SE, et al. Among authors: kampmann m. Elife. 2019 May 31;8:e46595. doi: 10.7554/eLife.46595. Elife. 2019. PMID: 31149896 Free PMC article.

8

CRISPR Interference-Based Platform for Multimodal Genetic Screens in Human iPSC-Derived Neurons.

Tian R, Gachechiladze MA, Ludwig CH, Laurie MT, Hong JY, Nathaniel D, Prabhu AV, Fernandopulle MS, Patel R, Abshari M, Ward ME, Kampmann M. Tian R, et al. Among authors: kampmann m. Neuron. 2019 Oct 23;104(2):239-255.e12. doi: 10.1016/j.neuron.2019.07.014. Epub 2019 Aug 15. Neuron. 2019. PMID: 31422865 Free PMC article.

9

Compromised function of the ESCRT pathway promotes endolysosomal escape of tau seeds and propagation of tau aggregation.

Chen JJ, Nathaniel DL, Raghavan P, Nelson M, Tian R, Tse E, Hong JY, See SK, Mok SA, Hein MY, Southworth DR, Grinberg LT, Gestwicki JE, Leonetti MD, Kampmann M. Chen JJ, et al. Among authors: kampmann m. J Biol Chem. 2019 Dec 13;294(50):18952-18966. doi: 10.1074/jbc.RA119.009432. Epub 2019 Oct 2. J Biol Chem. 2019. PMID: 31578281 Free PMC article.

10

Mitochondrial stress is relayed to the cytosol by an OMA1-DELE1-HRI pathway.

Guo X, Aviles G, Liu Y, Tian R, Unger BA, Lin YT, Wiita AP, Xu K, Correia MA, Kampmann M. Guo X, et al. Among authors: kampmann m. Nature. 2020 Mar;579(7799):427-432. doi: 10.1038/s41586-020-2078-2. Epub 2020 Mar 4. Nature. 2020. PMID: 32132707 Free PMC article.

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