Moore ML - Search Results

1

Novel vasopressin analogues that help define a minimum effective antagonist pharmacophore.

Huffman WF, Ali FE, Bryan WM, Callahan JF, Moore ML, Silvestri JS, Yim NC, Kinter LB, McDonald JE, Ashton-Shue D, et al. Huffman WF, et al. Among authors: moore ml. J Med Chem. 1985 Dec;28(12):1759-60. doi: 10.1021/jm00150a003. J Med Chem. 1985. PMID: 2933517 No abstract available.

2

Structure-activity relationships of novel vasopressin antagonists containing C-terminal diaminoalkanes and (aminoalkyl)guanidines.

Callahan JF, Ashton-Shue D, Bryan HG, Bryan WM, Heckman GD, Kinter LB, McDonald JE, Moore ML, Schmidt DB, Silvestri JS, et al. Callahan JF, et al. Among authors: moore ml. J Med Chem. 1989 Feb;32(2):391-6. doi: 10.1021/jm00122a017. J Med Chem. 1989. PMID: 2521519

3

Potent vasopressin antagonists lacking the proline residue at position 7.

Ali FE, Bryan W, Chang HL, Huffman WF, Moore ML, Heckman G, Kinter LB, McDonald J, Schmidt D, Shue D, et al. Ali FE, et al. Among authors: moore ml. J Med Chem. 1986 Jun;29(6):984-8. doi: 10.1021/jm00156a015. J Med Chem. 1986. PMID: 2940368

4

Potent antagonists of vasopressin antidiuretic activity that lack the beta,beta-cyclopentamethylene-beta-mercaptopropionic acid substitution at position 1.

Yim NC, Moore ML, Huffman WF, Bryan HG, Chang HL, Kinter LB, Edwards R, Stassen FL, Schmidt D, Heckman G. Yim NC, et al. Among authors: moore ml. J Med Chem. 1986 Dec;29(12):2425-6. doi: 10.1021/jm00162a001. J Med Chem. 1986. PMID: 2946863 No abstract available.

5

Design, synthesis, and biological activity of a peptide mimic of vasopressin.

Bryan WM, Hempel JC, Huffman WF, Marshall GR, Moore ML, Silvestri J, Stassen FL, Stefankiewicz JS, Sulat L, Webb RL. Bryan WM, et al. Among authors: moore ml. J Med Chem. 1988 Apr;31(4):742-4. doi: 10.1021/jm00399a009. J Med Chem. 1988. PMID: 2965243

6

A minor modification of residue 1 in potent vasopressin antagonists dramatically reduces agonist activity.

Huffman WF, Albrightson-Winslow C, Brickson B, Bryan HG, Caldwell N, Dytko G, Eggleston DS, Kinter LB, Moore ML, Newlander KA, et al. Huffman WF, et al. Among authors: moore ml. J Med Chem. 1989 Apr;32(4):880-4. doi: 10.1021/jm00124a025. J Med Chem. 1989. PMID: 2522994

7

Cyclic enkephalin analogues containing alpha-amino-beta-mercapto-beta,beta-pentamethylenepropionic acid at positions 2 or 5.

Bryan WM, Callahan JF, Codd EE, Lemieux C, Moore ML, Schiller PW, Walker RF, Huffman WF. Bryan WM, et al. Among authors: moore ml. J Med Chem. 1989 Feb;32(2):302-4. doi: 10.1021/jm00122a005. J Med Chem. 1989. PMID: 2536436

8

Vasopressin antagonist analogs modified at position 7.

Moore ML, Greene H, Huffman WF, Stassen F, Stefankiewicz J, Sulat L, Heckman G, Schmidt D, Kinter L, McDonald J, et al. Moore ML, et al. Int J Pept Protein Res. 1986 Oct;28(4):379-85. doi: 10.1111/j.1399-3011.1986.tb03269.x. Int J Pept Protein Res. 1986. PMID: 2947871

9

Dicarbavasopressin antagonist analogues exhibit reduced in vivo agonist activity.

Moore ML, Albrightson C, Brickson B, Bryan HG, Caldwell N, Callahan JF, Foster J, Kinter LB, Newlander KA, Schmidt DB, et al. Moore ML, et al. J Med Chem. 1988 Aug;31(8):1487-9. doi: 10.1021/jm00403a001. J Med Chem. 1988. PMID: 3397986 No abstract available.

10

A novel constrained reduced-amide inhibitor of HIV-1 protease derived from the sequential incorporation of gamma-turn mimetics into a model substrate.

Newlander KA, Callahan JF, Moore ML, Tomaszek TA Jr, Huffman WF. Newlander KA, et al. Among authors: moore ml. J Med Chem. 1993 Aug 6;36(16):2321-31. doi: 10.1021/jm00068a008. J Med Chem. 1993. PMID: 8360876

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