Hu L - Search Results

1

Design, synthesis and biological evaluation of LX2343 derivatives as neuroprotective agents for the treatment of Alzheimer's disease.

Sun G, Wang J, Guo X, Lei M, Zhang Y, Wang X, Shen X, Hu L. Sun G, et al. Among authors: hu l. Eur J Med Chem. 2018 Feb 10;145:622-633. doi: 10.1016/j.ejmech.2017.12.080. Epub 2018 Jan 2. Eur J Med Chem. 2018. PMID: 29339255

2

Synthesis and biological evaluation of arctigenin ester and ether derivatives as activators of AMPK.

Shen S, Zhuang J, Chen Y, Lei M, Chen J, Shen X, Hu L. Shen S, et al. Among authors: hu l. Bioorg Med Chem. 2013 Jul 1;21(13):3882-93. doi: 10.1016/j.bmc.2013.04.010. Epub 2013 Apr 18. Bioorg Med Chem. 2013. PMID: 23673223 Free article.

3

Design, synthesis, and SAR of embelin analogues as the inhibitors of PAI-1 (plasminogen activator inhibitor-1).

Chen F, Zhang G, Hong Z, Lin Z, Lei M, Huang M, Hu L. Chen F, et al. Among authors: hu l. Bioorg Med Chem Lett. 2014 May 15;24(10):2379-82. doi: 10.1016/j.bmcl.2014.03.045. Epub 2014 Mar 24. Bioorg Med Chem Lett. 2014. PMID: 24731276

4

Synthesis and cytotoxicity evaluation of 4-amino-4-dehydroxylarctigenin derivatives in glucose-starved A549 tumor cells.

Lei M, Gan X, Zhao K, Yu Q, Hu L. Lei M, et al. Among authors: hu l. Bioorg Med Chem Lett. 2015 Feb 1;25(3):435-7. doi: 10.1016/j.bmcl.2014.12.061. Epub 2014 Dec 24. Bioorg Med Chem Lett. 2015. PMID: 25571795

5

Synthesis and decreasing Aβ content evaluation of arctigenin-4-yl carbamate derivatives.

Xu X, Li C, Lei M, Zhu Z, Yan J, Shen X, Hu L. Xu X, et al. Among authors: hu l. Bioorg Med Chem Lett. 2016 Jul 1;26(13):2988-2991. doi: 10.1016/j.bmcl.2016.05.028. Epub 2016 May 10. Bioorg Med Chem Lett. 2016. PMID: 27212069

6

Design, synthesis and biological evaluation of indolin-2-one-based derivatives as potent, selective and efficacious inhibitors of FMS-like tyrosine kinase3 (FLT3).

Ma F, Liu P, Lei M, Liu J, Wang H, Zhao S, Hu L. Ma F, et al. Among authors: hu l. Eur J Med Chem. 2017 Feb 15;127:72-86. doi: 10.1016/j.ejmech.2016.12.038. Epub 2016 Dec 21. Eur J Med Chem. 2017. PMID: 28038328

7

Synthesis and glucose-stimulate insulin secretion (GSIS) evaluation of vindoline derivatives.

Xiao C, Tian Y, Lei M, Chen F, Gan X, Yao X, Shen X, Chen J, Hu L. Xiao C, et al. Among authors: hu l. Bioorg Med Chem Lett. 2017 Mar 1;27(5):1316-1318. doi: 10.1016/j.bmcl.2016.09.064. Epub 2016 Sep 28. Bioorg Med Chem Lett. 2017. PMID: 28162858

8

Discovery and structure-activity relationships study of thieno[2,3-b]pyridine analogues as hepatic gluconeogenesis inhibitors.

Ma F, Liu J, Zhou T, Lei M, Chen J, Wang X, Zhang Y, Shen X, Hu L. Ma F, et al. Among authors: hu l. Eur J Med Chem. 2018 May 25;152:307-317. doi: 10.1016/j.ejmech.2018.04.028. Epub 2018 Apr 24. Eur J Med Chem. 2018. PMID: 29733999

9

Design, synthesis and biological evaluation of mogrol derivatives as a novel class of AMPKα2β1γ1 activators.

Wang J, Liu J, Xie Z, Li J, Li J, Hu L. Wang J, et al. Among authors: hu l. Bioorg Med Chem Lett. 2020 Jan 15;30(2):126790. doi: 10.1016/j.bmcl.2019.126790. Epub 2019 Nov 9. Bioorg Med Chem Lett. 2020. PMID: 31744674

10

Design, synthesis and biological evaluation of vincamine derivatives as potential pancreatic β-cells protective agents for the treatment of type 2 diabetes mellitus.

Wang J, Lv X, Xu J, Liu X, Du T, Sun G, Chen J, Shen X, Wang J, Hu L. Wang J, et al. Among authors: hu l. Eur J Med Chem. 2020 Feb 15;188:111976. doi: 10.1016/j.ejmech.2019.111976. Epub 2019 Dec 25. Eur J Med Chem. 2020. PMID: 31918073

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