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Induction of alpha-synuclein pathology in the enteric nervous system of the rat and non-human primate results in gastrointestinal dysmotility and transient CNS pathology.
Manfredsson FP, Luk KC, Benskey MJ, Gezer A, Garcia J, Kuhn NC, Sandoval IM, Patterson JR, O'Mara A, Yonkers R, Kordower JH. Manfredsson FP, et al. Among authors: kuhn nc. Neurobiol Dis. 2018 Apr;112:106-118. doi: 10.1016/j.nbd.2018.01.008. Epub 2018 Jan 16. Neurobiol Dis. 2018. PMID: 29341898 Free PMC article.
Basic Concepts in Viral Vector-Mediated Gene Therapy.
Benskey MJ, Sandoval IM, Miller K, Sellnow RL, Gezer A, Kuhn NC, Vashon R, Manfredsson FP. Benskey MJ, et al. Among authors: kuhn nc. Methods Mol Biol. 2019;1937:3-26. doi: 10.1007/978-1-4939-9065-8_1. Methods Mol Biol. 2019. PMID: 30706387
Developmental exposure to the organochlorine pesticide dieldrin causes male-specific exacerbation of α-synuclein-preformed fibril-induced toxicity and motor deficits.
Gezer AO, Kochmanski J, VanOeveren SE, Cole-Strauss A, Kemp CJ, Patterson JR, Miller KM, Kuhn NC, Herman DE, McIntire A, Lipton JW, Luk KC, Fleming SM, Sortwell CE, Bernstein AI. Gezer AO, et al. Among authors: kuhn nc. Neurobiol Dis. 2020 Jul;141:104947. doi: 10.1016/j.nbd.2020.104947. Epub 2020 May 15. Neurobiol Dis. 2020. PMID: 32422283 Free PMC article.
Epigenetic inactivation of the autophagy-lysosomal system in appendix in Parkinson's disease.
Gordevicius J, Li P, Marshall LL, Killinger BA, Lang S, Ensink E, Kuhn NC, Cui W, Maroof N, Lauria R, Rueb C, Siebourg-Polster J, Maliver P, Lamp J, Vega I, Manfredsson FP, Britschgi M, Labrie V. Gordevicius J, et al. Among authors: kuhn nc. Nat Commun. 2021 Aug 26;12(1):5134. doi: 10.1038/s41467-021-25474-x. Nat Commun. 2021. PMID: 34446734 Free PMC article.
Developmental exposure to the Parkinson's disease-associated organochlorine pesticide dieldrin alters dopamine neurotransmission in α-synuclein pre-formed fibril (PFF)-injected mice.
Boyd SL, Kuhn NC, Patterson JR, Stoll AC, Zimmerman SA, Kolanowski MR, Neubecker JJ, Luk KC, Ramsson ES, Sortwell CE, Bernstein AI. Boyd SL, et al. Among authors: kuhn nc. Toxicol Sci. 2023 Oct 30;196(1):99-111. doi: 10.1093/toxsci/kfad086. Toxicol Sci. 2023. PMID: 37607008 Free PMC article.
18 results