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Nonclinical Safety Evaluation of scAAV8-RLBP1 for Treatment of RLBP1 Retinitis Pigmentosa.
MacLachlan TK, Milton MN, Turner O, Tukov F, Choi VW, Penraat J, Delmotte MH, Michaut L, Jaffee BD, Bigelow CE. MacLachlan TK, et al. Among authors: turner o. Mol Ther Methods Clin Dev. 2017 Dec 22;8:105-120. doi: 10.1016/j.omtm.2017.12.001. eCollection 2018 Mar 16. Mol Ther Methods Clin Dev. 2017. PMID: 29359172 Free PMC article.
AAV-mediated RLBP1 gene therapy improves the rate of dark adaptation in Rlbp1 knockout mice.
Choi VW, Bigelow CE, McGee TL, Gujar AN, Li H, Hanks SM, Vrouvlianis J, Maker M, Leehy B, Zhang Y, Aranda J, Bounoutas G, Demirs JT, Yang J, Ornberg R, Wang Y, Martin W, Stout KR, Argentieri G, Grosenstein P, Diaz D, Turner O, Jaffee BD, Police SR, Dryja TP. Choi VW, et al. Among authors: turner o. Mol Ther Methods Clin Dev. 2015 Jul 8;2:15022. doi: 10.1038/mtm.2015.22. eCollection 2015. Mol Ther Methods Clin Dev. 2015. PMID: 26199951 Free PMC article.
Anti-brolucizumab immune response as one prerequisite for rare retinal vasculitis/retinal vascular occlusion adverse events.
Karle AC, Wrobel MB, Koepke S, Gutknecht M, Gottlieb S, Christen B, Rubic-Schneider T, Pruimboom-Brees I, Leber XC, Scharenberg M, Maciejewski B, Turner O, Saravanan C, Huet F, Littlewood-Evans A, Clemens A, Grosskreutz CL, Kearns JD, Mehan P, Schmouder RL, Sasseville V, Brees D. Karle AC, et al. Among authors: turner o. Sci Transl Med. 2023 Feb;15(681):eabq5241. doi: 10.1126/scitranslmed.abq5241. Epub 2023 Feb 1. Sci Transl Med. 2023. PMID: 36724238
Ocular toxicity of AUY922 in pigmented and albino rats.
Roman D, VerHoeve J, Schadt H, Vicart A, Walker UJ, Turner O, Richardson TA, Wolford ST, Miller PE, Zhou W, Lu H, Akimov M, Kluwe W. Roman D, et al. Among authors: turner o. Toxicol Appl Pharmacol. 2016 Oct 15;309:55-62. doi: 10.1016/j.taap.2016.08.025. Epub 2016 Aug 28. Toxicol Appl Pharmacol. 2016. PMID: 27576608
111 results