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Page 1
Integration of Multi-omics Data from Mouse Diversity Panel Highlights Mitochondrial Dysfunction in Non-alcoholic Fatty Liver Disease.
Chella Krishnan K, Kurt Z, Barrere-Cain R, Sabir S, Das A, Floyd R, Vergnes L, Zhao Y, Che N, Charugundla S, Qi H, Zhou Z, Meng Y, Pan C, Seldin MM, Norheim F, Hui S, Reue K, Lusis AJ, Yang X. Chella Krishnan K, et al. Cell Syst. 2018 Jan 24;6(1):103-115.e7. doi: 10.1016/j.cels.2017.12.006. Epub 2018 Jan 18. Cell Syst. 2018. PMID: 29361464 Free PMC article.
A Strategy for Discovery of Endocrine Interactions with Application to Whole-Body Metabolism.
Seldin MM, Koplev S, Rajbhandari P, Vergnes L, Rosenberg GM, Meng Y, Pan C, Phuong TMN, Gharakhanian R, Che N, Mäkinen S, Shih DM, Civelek M, Parks BW, Kim ED, Norheim F, Chella Krishnan K, Hasin-Brumshtein Y, Mehrabian M, Laakso M, Drevon CA, Koistinen HA, Tontonoz P, Reue K, Cantor RM, Björkegren JLM, Lusis AJ. Seldin MM, et al. Among authors: chella krishnan k. Cell Metab. 2018 May 1;27(5):1138-1155.e6. doi: 10.1016/j.cmet.2018.03.015. Cell Metab. 2018. PMID: 29719227 Free PMC article.
Genetic, dietary, and sex-specific regulation of hepatic ceramides and the relationship between hepatic ceramides and IR.
Norheim F, Bjellaas T, Hui ST, Chella Krishnan K, Lee J, Gupta S, Pan C, Hasin-Brumshtein Y, Parks BW, Li DY, Bui HH, Mosier M, Wu Y, Huertas-Vazquez A, Hazen SL, Gundersen TE, Mehrabian M, Tang WHW, Hevener AL, Drevon CA, Lusis AJ. Norheim F, et al. Among authors: chella krishnan k. J Lipid Res. 2018 Jul;59(7):1164-1174. doi: 10.1194/jlr.M081398. Epub 2018 May 8. J Lipid Res. 2018. PMID: 29739864 Free PMC article.
The Genetic Architecture of Diet-Induced Hepatic Fibrosis in Mice.
Hui ST, Kurt Z, Tuominen I, Norheim F, C Davis R, Pan C, Dirks DL, Magyar CE, French SW, Chella Krishnan K, Sabir S, Campos-Pérez F, Méndez-Sánchez N, Macías-Kauffer L, León-Mimila P, Canizales-Quinteros S, Yang X, Beaven SW, Huertas-Vazquez A, Lusis AJ. Hui ST, et al. Among authors: chella krishnan k. Hepatology. 2018 Dec;68(6):2182-2196. doi: 10.1002/hep.30113. Epub 2018 Nov 8. Hepatology. 2018. PMID: 29907965 Free PMC article.
Sex differences in metabolism and cardiometabolic disorders.
Chella Krishnan K, Mehrabian M, Lusis AJ. Chella Krishnan K, et al. Curr Opin Lipidol. 2018 Oct;29(5):404-410. doi: 10.1097/MOL.0000000000000536. Curr Opin Lipidol. 2018. PMID: 30156571 Free PMC article. Review.
Gene-by-Sex Interactions in Mitochondrial Functions and Cardio-Metabolic Traits.
Norheim F, Hasin-Brumshtein Y, Vergnes L, Chella Krishnan K, Pan C, Seldin MM, Hui ST, Mehrabian M, Zhou Z, Gupta S, Parks BW, Walch A, Reue K, Hofmann SM, Arnold AP, Lusis AJ. Norheim F, et al. Among authors: chella krishnan k. Cell Metab. 2019 Apr 2;29(4):932-949.e4. doi: 10.1016/j.cmet.2018.12.013. Epub 2019 Jan 10. Cell Metab. 2019. PMID: 30639359 Free PMC article.
Sex-specific metabolic functions of adipose Lipocalin-2.
Chella Krishnan K, Sabir S, Shum M, Meng Y, Acín-Pérez R, Lang JM, Floyd RR, Vergnes L, Seldin MM, Fuqua BK, Jayasekera DW, Nand SK, Anum DC, Pan C, Stiles L, Péterfy M, Reue K, Liesa M, Lusis AJ. Chella Krishnan K, et al. Mol Metab. 2019 Dec;30:30-47. doi: 10.1016/j.molmet.2019.09.009. Epub 2019 Sep 27. Mol Metab. 2019. PMID: 31767179 Free PMC article.
Liver Pyruvate Kinase Promotes NAFLD/NASH in Both Mice and Humans in a Sex-Specific Manner.
Chella Krishnan K, Floyd RR, Sabir S, Jayasekera DW, Leon-Mimila PV, Jones AE, Cortez AA, Shravah V, Péterfy M, Stiles L, Canizales-Quinteros S, Divakaruni AS, Huertas-Vazquez A, Lusis AJ. Chella Krishnan K, et al. Cell Mol Gastroenterol Hepatol. 2021;11(2):389-406. doi: 10.1016/j.jcmgh.2020.09.004. Epub 2020 Sep 14. Cell Mol Gastroenterol Hepatol. 2021. PMID: 32942044 Free PMC article.
Genetic regulation of liver lipids in a mouse model of insulin resistance and hepatic steatosis.
Norheim F, Chella Krishnan K, Bjellaas T, Vergnes L, Pan C, Parks BW, Meng Y, Lang J, Ward JA, Reue K, Mehrabian M, Gundersen TE, Péterfy M, Dalen KT, Drevon CA, Hui ST, Lusis AJ, Seldin MM. Norheim F, et al. Among authors: chella krishnan k. Mol Syst Biol. 2021 Jan;17(1):e9684. doi: 10.15252/msb.20209684. Mol Syst Biol. 2021. PMID: 33417276 Free PMC article.
ABCB10 exports mitochondrial biliverdin, driving metabolic maladaptation in obesity.
Shum M, Shintre CA, Althoff T, Gutierrez V, Segawa M, Saxberg AD, Martinez M, Adamson R, Young MR, Faust B, Gharakhanian R, Su S, Chella Krishnan K, Mahdaviani K, Veliova M, Wolf DM, Ngo J, Nocito L, Stiles L, Abramson J, Lusis AJ, Hevener AL, Zoghbi ME, Carpenter EP, Liesa M. Shum M, et al. Among authors: chella krishnan k. Sci Transl Med. 2021 May 19;13(594):eabd1869. doi: 10.1126/scitranslmed.abd1869. Sci Transl Med. 2021. PMID: 34011630 Free PMC article.
21 results