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Targeting mPGES-1 by a Combinatorial Approach: Identification of the Aminobenzothiazole Scaffold to Suppress PGE2 Levels.
Chini MG, Giordano A, Potenza M, Terracciano S, Fischer K, Vaccaro MC, Colarusso E, Bruno I, Riccio R, Koeberle A, Werz O, Bifulco G. Chini MG, et al. Among authors: potenza m. ACS Med Chem Lett. 2020 Mar 5;11(5):783-789. doi: 10.1021/acsmedchemlett.9b00618. eCollection 2020 May 14. ACS Med Chem Lett. 2020. PMID: 32435385 Free PMC article.
Inverse Virtual Screening for the rapid re-evaluation of the presumed biological safe profile of natural products. The case of steviol from Stevia rebaudiana glycosides on farnesoid X receptor (FXR).
Potenza M, Cavalluzzi MM, Milani G, Lauro G, Carino A, Roselli R, Fiorucci S, Zampella A, Pierri CL, Lentini G, Bifulco G. Potenza M, et al. Bioorg Chem. 2021 Jun;111:104897. doi: 10.1016/j.bioorg.2021.104897. Epub 2021 Apr 8. Bioorg Chem. 2021. PMID: 33901797
Structure-based screening for the discovery of 1,2,4-oxadiazoles as promising hits for the development of new anti-inflammatory agents interfering with eicosanoid biosynthesis pathways.
Potenza M, Sciarretta M, Chini MG, Saviano A, Maione F, D'Auria MV, De Marino S, Giordano A, Hofstetter RK, Festa C, Werz O, Bifulco G. Potenza M, et al. Eur J Med Chem. 2021 Nov 15;224:113693. doi: 10.1016/j.ejmech.2021.113693. Epub 2021 Jul 13. Eur J Med Chem. 2021. PMID: 34315041
Identification of 2-Aminoacyl-1,3,4-thiadiazoles as Prostaglandin E2 and Leukotriene Biosynthesis Inhibitors.
Potenza M, Giordano A, Chini MG, Saviano A, Kretzer C, Raucci F, Russo M, Lauro G, Terracciano S, Bruno I, Iorizzi M, Hofstetter RK, Pace S, Maione F, Werz O, Bifulco G. Potenza M, et al. ACS Med Chem Lett. 2022 Dec 9;14(1):26-34. doi: 10.1021/acsmedchemlett.2c00343. eCollection 2023 Jan 12. ACS Med Chem Lett. 2022. PMID: 36655121 Free PMC article.
997 results