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NT113, a pan-ERBB inhibitor with high brain penetrance, inhibits the growth of glioblastoma xenografts with EGFR amplification.
Yoshida Y, Ozawa T, Yao TW, Shen W, Brown D, Parsa AT, Raizer JJ, Cheng SY, Stegh AH, Mazar AP, Giles FJ, Sarkaria JN, Butowski N, Nicolaides T, James CD. Yoshida Y, et al. Among authors: giles fj. Mol Cancer Ther. 2014 Dec;13(12):2919-29. doi: 10.1158/1535-7163.MCT-14-0306. Epub 2014 Oct 13. Mol Cancer Ther. 2014. PMID: 25313012 Free PMC article.
Synthetic high-density lipoprotein-like nanoparticles for cancer therapy.
Foit L, Giles FJ, Gordon LI, Thaxton CS. Foit L, et al. Among authors: giles fj. Expert Rev Anticancer Ther. 2015 Jan;15(1):27-34. doi: 10.1586/14737140.2015.990889. Epub 2014 Dec 9. Expert Rev Anticancer Ther. 2015. PMID: 25487833 Free PMC article. Review.
Repurposing metformin for cancer treatment: current clinical studies.
Chae YK, Arya A, Malecek MK, Shin DS, Carneiro B, Chandra S, Kaplan J, Kalyan A, Altman JK, Platanias L, Giles F. Chae YK, et al. Oncotarget. 2016 Jun 28;7(26):40767-40780. doi: 10.18632/oncotarget.8194. Oncotarget. 2016. PMID: 27004404 Free PMC article. Review.
Genomic landscape of DNA repair genes in cancer.
Chae YK, Anker JF, Carneiro BA, Chandra S, Kaplan J, Kalyan A, Santa-Maria CA, Platanias LC, Giles FJ. Chae YK, et al. Among authors: giles fj. Oncotarget. 2016 Apr 26;7(17):23312-21. doi: 10.18632/oncotarget.8196. Oncotarget. 2016. PMID: 27004405 Free PMC article.
The challenge of developmental therapeutics for adrenocortical carcinoma.
Costa R, Carneiro BA, Tavora F, Pai SG, Kaplan JB, Chae YK, Chandra S, Kopp PA, Giles FJ. Costa R, et al. Among authors: giles fj. Oncotarget. 2016 Jul 19;7(29):46734-46749. doi: 10.18632/oncotarget.8774. Oncotarget. 2016. PMID: 27102148 Free PMC article. Review.
653 results