Spencer PS - Search Results

1

Proteomic alterations of brain subcellular organelles caused by low-dose copper exposure: implication for Alzheimer's disease.

Yu H, Wang D, Zou L, Zhang Z, Xu H, Zhu F, Ren X, Xu B, Yuan J, Liu J, Spencer PS, Yang X. Yu H, et al. Among authors: spencer ps. Arch Toxicol. 2018 Apr;92(4):1363-1382. doi: 10.1007/s00204-018-2163-6. Epub 2018 Jan 30. Arch Toxicol. 2018. PMID: 29383422

2

Mitochondrial Molecular Abnormalities Revealed by Proteomic Analysis of Hippocampal Organelles of Mice Triple Transgenic for Alzheimer Disease.

Yu H, Lin X, Wang D, Zhang Z, Guo Y, Ren X, Xu B, Yuan J, Liu J, Spencer PS, Wang JZ, Yang X. Yu H, et al. Among authors: spencer ps. Front Mol Neurosci. 2018 Mar 9;11:74. doi: 10.3389/fnmol.2018.00074. eCollection 2018. Front Mol Neurosci. 2018. PMID: 29593495 Free PMC article.

3

TRPC1 Deletion Causes Striatal Neuronal Cell Apoptosis and Proteomic Alterations in Mice.

Wang D, Yu H, Xu B, Xu H, Zhang Z, Ren X, Yuan J, Liu J, Guo Y, Spencer PS, Yang X. Wang D, et al. Among authors: spencer ps. Front Aging Neurosci. 2018 Mar 20;10:72. doi: 10.3389/fnagi.2018.00072. eCollection 2018. Front Aging Neurosci. 2018. PMID: 29615894 Free PMC article.

4

The Prenylflavonoid Xanthohumol Reduces Alzheimer-Like Changes and Modulates Multiple Pathogenic Molecular Pathways in the Neuro2a/APP_swe Cell Model of AD.

Huang X, Wang J, Chen X, Liu P, Wang S, Song F, Zhang Z, Zhu F, Huang X, Liu J, Song G, Spencer PS, Yang X. Huang X, et al. Among authors: spencer ps. Front Pharmacol. 2018 Apr 4;9:199. doi: 10.3389/fphar.2018.00199. eCollection 2018. Front Pharmacol. 2018. PMID: 29670521 Free PMC article.

5

The Isoquinoline Alkaloid Dauricine Targets Multiple Molecular Pathways to Ameliorate Alzheimer-Like Pathological Changes In Vitro.

Liu P, Chen X, Zhou H, Wang L, Zhang Z, Ren X, Zhu F, Guo Y, Huang X, Liu J, Spencer PS, Yang X. Liu P, et al. Among authors: spencer ps. Oxid Med Cell Longev. 2018 Jul 2;2018:2025914. doi: 10.1155/2018/2025914. eCollection 2018. Oxid Med Cell Longev. 2018. PMID: 30057671 Free PMC article.

6

Low-dose oral copper treatment changes the hippocampal phosphoproteomic profile and perturbs mitochondrial function in a mouse model of Alzheimer's disease.

Chen C, Jiang X, Li Y, Yu H, Li S, Zhang Z, Xu H, Yang Y, Liu G, Zhu F, Ren X, Zou L, Xu B, Liu J, Spencer PS, Yang X. Chen C, et al. Among authors: spencer ps. Free Radic Biol Med. 2019 May 1;135:144-156. doi: 10.1016/j.freeradbiomed.2019.03.002. Epub 2019 Mar 9. Free Radic Biol Med. 2019. PMID: 30862541

7

Dysregulation of Myosin Complex and Striated Muscle Contraction Pathway in the Brains of ALS-SOD1 Model Mice.

Xu B, Zheng C, Chen X, Zhang Z, Liu J, Spencer P, Yang X. Xu B, et al. ACS Chem Neurosci. 2019 May 15;10(5):2408-2417. doi: 10.1021/acschemneuro.8b00704. Epub 2019 Mar 28. ACS Chem Neurosci. 2019. PMID: 30889949

8

Flavanol-rich lychee fruit extract substantially reduces progressive cognitive and molecular deficits in a triple-transgenic animal model of Alzheimer disease.

Chen X, Xu B, Nie L, He K, Zhou L, Huang X, Spencer P, Yang X, Liu J. Chen X, et al. Nutr Neurosci. 2021 Sep;24(9):720-734. doi: 10.1080/1028415X.2019.1673527. Epub 2019 Oct 11. Nutr Neurosci. 2021. PMID: 31603034

9

Proteomic Profile of Mouse Brain Aging Contributions to Mitochondrial Dysfunction, DNA Oxidative Damage, Loss of Neurotrophic Factor, and Synaptic and Ribosomal Proteins.

Li Y, Yu H, Chen C, Li S, Zhang Z, Xu H, Zhu F, Liu J, Spencer PS, Dai Z, Yang X. Li Y, et al. Among authors: spencer ps. Oxid Med Cell Longev. 2020 Jun 9;2020:5408452. doi: 10.1155/2020/5408452. eCollection 2020. Oxid Med Cell Longev. 2020. PMID: 32587661 Free PMC article.

10

Diabetes mellitus is associated with elevated urinary pyrrole markers of γ-diketones known to cause axonal neuropathy.

Chen X, Liu W, Wang L, Lin D, Nie L, He K, Guo Z, Zhu F, Feng W, Liu W, Yuan J, Yang X, Spencer P, Liu J. Chen X, et al. BMJ Open Diabetes Res Care. 2020 Sep;8(1):e001575. doi: 10.1136/bmjdrc-2020-001575. BMJ Open Diabetes Res Care. 2020. PMID: 32912928 Free PMC article.

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