Discovery of STX-721, a Covalent, Potent, and Highly Mutant-Selective EGFR/HER2 Exon20 Insertion Inhibitor for the Treatment of Non-Small Cell Lung Cancer.
Milgram BC, Borrelli DR, Brooijmans N, Henderson JA, Hilbert BJ, Huff MR, Ito T, Jackson EL, Jonsson P, Ladd B, O'Hearn EL, Pagliarini RA, Roberts SA, Ronseaux S, Stuart DD, Wang W, Guzman-Perez A.
Milgram BC, et al. Among authors: huff mr.
J Med Chem. 2025 Jan 17. doi: 10.1021/acs.jmedchem.4c02377. Online ahead of print.
J Med Chem. 2025.
PMID: 39824516