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Blocking extracellular activation of myostatin as a strategy for treating muscle wasting.
Sci Rep. 2018 Feb 2;8(1):2292. doi: 10.1038/s41598-018-20524-9.
Sci Rep. 2018.
PMID: 29396542
Free PMC article.
Tolloid cleavage activates latent GDF8 by priming the pro-complex for dissociation.
Le VQ, Iacob RE, Tian Y, McConaughy W, Jackson J, Su Y, Zhao B, Engen JR, Pirruccello-Straub M, Springer TA.
Le VQ, et al. Among authors: mcconaughy w.
EMBO J. 2018 Feb 1;37(3):384-397. doi: 10.15252/embj.201797931. Epub 2018 Jan 17.
EMBO J. 2018.
PMID: 29343545
Free PMC article.
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Differentiated agonistic antibody targeting CD137 eradicates large tumors without hepatotoxicity.
Eskiocak U, Guzman W, Wolf B, Cummings C, Milling L, Wu HJ, Ophir M, Lambden C, Bakhru P, Gilmore DC, Ottinger S, Liu L, McConaughy WK, He SQ, Wang C, Leung CL, Lajoie J, Carson WF 4th, Zizlsperger N, Schmidt MM, Anderson AC, Bobrowicz P, Schuetz TJ, Tighe R.
Eskiocak U, et al. Among authors: mcconaughy wk.
JCI Insight. 2020 Mar 12;5(5):e133647. doi: 10.1172/jci.insight.133647.
JCI Insight. 2020.
PMID: 32161196
Free PMC article.
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ANGPTL7 and Its Role in IOP and Glaucoma.
Brown SF, Nguyen H, Mzyk P, De Ieso ML, Unser AM, Brown I, Ramesh P, Afzaal H, Ahmed F, Torrejon KY, Nhan A, Markrush D, Daly T, Knecht E, McConaughy W, Halmos S, Liu ZL, Rennard R, Peterson A, Stamer WD.
Brown SF, et al. Among authors: mcconaughy w.
Invest Ophthalmol Vis Sci. 2024 Mar 5;65(3):22. doi: 10.1167/iovs.65.3.22.
Invest Ophthalmol Vis Sci. 2024.
PMID: 38497513
Free PMC article.
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