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Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance.
Fazakerley DJ, Chaudhuri R, Yang P, Maghzal GJ, Thomas KC, Krycer JR, Humphrey SJ, Parker BL, Fisher-Wellman KH, Meoli CC, Hoffman NJ, Diskin C, Burchfield JG, Cowley MJ, Kaplan W, Modrusan Z, Kolumam G, Yang JY, Chen DL, Samocha-Bonet D, Greenfield JR, Hoehn KL, Stocker R, James DE. Fazakerley DJ, et al. Among authors: stocker r. Elife. 2018 Feb 6;7:e32111. doi: 10.7554/eLife.32111. Elife. 2018. PMID: 29402381 Free PMC article.
Insulin resistance is a cellular antioxidant defense mechanism.
Hoehn KL, Salmon AB, Hohnen-Behrens C, Turner N, Hoy AJ, Maghzal GJ, Stocker R, Van Remmen H, Kraegen EW, Cooney GJ, Richardson AR, James DE. Hoehn KL, et al. Among authors: stocker r. Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17787-92. doi: 10.1073/pnas.0902380106. Epub 2009 Sep 30. Proc Natl Acad Sci U S A. 2009. PMID: 19805130 Free PMC article.
Succinobucol induces apoptosis in vascular smooth muscle cells.
Midwinter RG, Maghzal GJ, Dennis JM, Wu BJ, Cai H, Kapralov AA, Belikova NA, Tyurina YY, Dong LF, Khachigian L, Neuzil J, Kagan VE, Stocker R. Midwinter RG, et al. Among authors: stocker r. Free Radic Biol Med. 2012 Mar 1;52(5):871-9. doi: 10.1016/j.freeradbiomed.2011.11.029. Epub 2011 Dec 21. Free Radic Biol Med. 2012. PMID: 22203369
756 results