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Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance.
Fazakerley DJ, Chaudhuri R, Yang P, Maghzal GJ, Thomas KC, Krycer JR, Humphrey SJ, Parker BL, Fisher-Wellman KH, Meoli CC, Hoffman NJ, Diskin C, Burchfield JG, Cowley MJ, Kaplan W, Modrusan Z, Kolumam G, Yang JY, Chen DL, Samocha-Bonet D, Greenfield JR, Hoehn KL, Stocker R, James DE. Fazakerley DJ, et al. Among authors: yang p, yang jy. Elife. 2018 Feb 6;7:e32111. doi: 10.7554/eLife.32111. Elife. 2018. PMID: 29402381 Free PMC article.
Dynamic adipocyte phosphoproteome reveals that Akt directly regulates mTORC2.
Humphrey SJ, Yang G, Yang P, Fazakerley DJ, Stöckli J, Yang JY, James DE. Humphrey SJ, et al. Among authors: yang p, yang jy, yang g. Cell Metab. 2013 Jun 4;17(6):1009-1020. doi: 10.1016/j.cmet.2013.04.010. Epub 2013 May 16. Cell Metab. 2013. PMID: 23684622 Free PMC article.
Global Phosphoproteomic Analysis of Human Skeletal Muscle Reveals a Network of Exercise-Regulated Kinases and AMPK Substrates.
Hoffman NJ, Parker BL, Chaudhuri R, Fisher-Wellman KH, Kleinert M, Humphrey SJ, Yang P, Holliday M, Trefely S, Fazakerley DJ, Stöckli J, Burchfield JG, Jensen TE, Jothi R, Kiens B, Wojtaszewski JF, Richter EA, James DE. Hoffman NJ, et al. Among authors: yang p. Cell Metab. 2015 Nov 3;22(5):922-35. doi: 10.1016/j.cmet.2015.09.001. Epub 2015 Oct 1. Cell Metab. 2015. PMID: 26437602 Free PMC article.
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