Brady SF - Search Results

1

An Optimized Synthetic-Bioinformatic Natural Product Antibiotic Sterilizes Multidrug-Resistant Acinetobacter baumannii-Infected Wounds.

Vila-Farres X, Chu J, Ternei MA, Lemetre C, Park S, Perlin DS, Brady SF. Vila-Farres X, et al. Among authors: brady sf. mSphere. 2018 Jan 24;3(1):e00528-17. doi: 10.1128/mSphere.00528-17. eCollection 2018 Jan-Feb. mSphere. 2018. PMID: 29404414 Free PMC article.

2

Malleilactone, a polyketide synthase-derived virulence factor encoded by the cryptic secondary metabolome of Burkholderia pseudomallei group pathogens.

Biggins JB, Ternei MA, Brady SF. Biggins JB, et al. Among authors: brady sf. J Am Chem Soc. 2012 Aug 15;134(32):13192-5. doi: 10.1021/ja3052156. Epub 2012 Aug 1. J Am Chem Soc. 2012. PMID: 22765305 Free PMC article.

3

Mapping gene clusters within arrayed metagenomic libraries to expand the structural diversity of biomedically relevant natural products.

Owen JG, Reddy BV, Ternei MA, Charlop-Powers Z, Calle PY, Kim JH, Brady SF. Owen JG, et al. Among authors: brady sf. Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):11797-802. doi: 10.1073/pnas.1222159110. Epub 2013 Jul 3. Proc Natl Acad Sci U S A. 2013. PMID: 23824289 Free PMC article.

4

Discovery and synthetic refactoring of tryptophan dimer gene clusters from the environment.

Chang FY, Ternei MA, Calle PY, Brady SF. Chang FY, et al. Among authors: brady sf. J Am Chem Soc. 2013 Nov 27;135(47):17906-12. doi: 10.1021/ja408683p. Epub 2013 Nov 14. J Am Chem Soc. 2013. PMID: 24171465 Free PMC article.

5

Chemical-biogeographic survey of secondary metabolism in soil.

Charlop-Powers Z, Owen JG, Reddy BV, Ternei MA, Brady SF. Charlop-Powers Z, et al. Among authors: brady sf. Proc Natl Acad Sci U S A. 2014 Mar 11;111(10):3757-62. doi: 10.1073/pnas.1318021111. Epub 2014 Feb 18. Proc Natl Acad Sci U S A. 2014. PMID: 24550451 Free PMC article.

6

The chemical arsenal of Burkholderia pseudomallei is essential for pathogenicity.

Biggins JB, Kang HS, Ternei MA, DeShazer D, Brady SF. Biggins JB, et al. Among authors: brady sf. J Am Chem Soc. 2014 Jul 2;136(26):9484-90. doi: 10.1021/ja504617n. Epub 2014 Jun 24. J Am Chem Soc. 2014. PMID: 24884988 Free PMC article.

7

Global biogeographic sampling of bacterial secondary metabolism.

Charlop-Powers Z, Owen JG, Reddy BV, Ternei MA, Guimarães DO, de Frias UA, Pupo MT, Seepe P, Feng Z, Brady SF. Charlop-Powers Z, et al. Among authors: brady sf. Elife. 2015 Jan 19;4:e05048. doi: 10.7554/eLife.05048. Elife. 2015. PMID: 25599565 Free PMC article.

8

Multiplexed metagenome mining using short DNA sequence tags facilitates targeted discovery of epoxyketone proteasome inhibitors.

Owen JG, Charlop-Powers Z, Smith AG, Ternei MA, Calle PY, Reddy BV, Montiel D, Brady SF. Owen JG, et al. Among authors: brady sf. Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):4221-6. doi: 10.1073/pnas.1501124112. Epub 2015 Mar 23. Proc Natl Acad Sci U S A. 2015. PMID: 25831524 Free PMC article.

9

Targeted metagenomics: finding rare tryptophan dimer natural products in the environment.

Chang FY, Ternei MA, Calle PY, Brady SF. Chang FY, et al. Among authors: brady sf. J Am Chem Soc. 2015 May 13;137(18):6044-52. doi: 10.1021/jacs.5b01968. Epub 2015 May 4. J Am Chem Soc. 2015. PMID: 25872030 Free PMC article.

10

Functional metagenomic discovery of bacterial effectors in the human microbiome and isolation of commendamide, a GPCR G2A/132 agonist.

Cohen LJ, Kang HS, Chu J, Huang YH, Gordon EA, Reddy BV, Ternei MA, Craig JW, Brady SF. Cohen LJ, et al. Among authors: brady sf. Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):E4825-34. doi: 10.1073/pnas.1508737112. Epub 2015 Aug 17. Proc Natl Acad Sci U S A. 2015. PMID: 26283367 Free PMC article.

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