Moghrabi WN - Search Results

1

The AU-rich element landscape across human transcriptome reveals a large proportion in introns and regulation by ELAVL1/HuR.

Bakheet T, Hitti E, Al-Saif M, Moghrabi WN, Khabar KSA. Bakheet T, et al. Among authors: moghrabi wn. Biochim Biophys Acta Gene Regul Mech. 2018 Feb;1861(2):167-177. doi: 10.1016/j.bbagrm.2017.12.006. Epub 2018 Feb 2. Biochim Biophys Acta Gene Regul Mech. 2018. PMID: 29413897 Free article.

2

Systematic Analysis of AU-Rich Element Expression in Cancer Reveals Common Functional Clusters Regulated by Key RNA-Binding Proteins.

Hitti E, Bakheet T, Al-Souhibani N, Moghrabi W, Al-Yahya S, Al-Ghamdi M, Al-Saif M, Shoukri MM, Lánczky A, Grépin R, Győrffy B, Pagès G, Khabar KS. Hitti E, et al. Cancer Res. 2016 Jul 15;76(14):4068-80. doi: 10.1158/0008-5472.CAN-15-3110. Epub 2016 May 17. Cancer Res. 2016. PMID: 27197193

3

A novel mechanism for variable phenotypic expressivity in Mendelian diseases uncovered by an AU-rich element (ARE)-creating mutation.

Patel N, Khan AO, Al-Saif M, Moghrabi WN, AlMaarik BM, Ibrahim N, Abdulwahab F, Hashem M, Alshidi T, Alobeid E, Alomar RA, Al-Harbi S, Abouelhoda M, Khabar KSA, Alkuraya FS. Patel N, et al. Among authors: moghrabi wn. Genome Biol. 2017 Jul 28;18(1):144. doi: 10.1186/s13059-017-1274-3. Genome Biol. 2017. PMID: 28754144 Free PMC article.

4

Bi-phased regulation of the post-transcriptional inflammatory response by Tristetraprolin levels.

Mahmoud L, Moghrabi W, Khabar KSA, Hitti EG. Mahmoud L, et al. RNA Biol. 2019 Mar;16(3):309-319. doi: 10.1080/15476286.2019.1572437. Epub 2019 Jan 28. RNA Biol. 2019. PMID: 30664390 Free PMC article.

5

Post-Transcriptional Inflammatory Response to Intracellular Bacterial c-di-AMP.

Mahmoud L, Abdulkarim AS, Kutbi S, Moghrabi W, Altwijri S, Khabar KSA, Hitti EG. Mahmoud L, et al. Front Immunol. 2020 Jan 17;10:3050. doi: 10.3389/fimmu.2019.03050. eCollection 2019. Front Immunol. 2020. PMID: 32010134 Free PMC article.

6

Kinome inhibition reveals a role for polo-like kinase 1 in targeting post-transcriptional control in cancer.

Al-Qahtani QH, Moghrabi WN, Al-Yahya S, Al-Haj L, Al-Saif M, Mahmoud L, Al-Mohanna F, Al-Souhibani N, Alaiya A, Hitti E, Khabar KSA. Al-Qahtani QH, et al. Among authors: moghrabi wn. Mol Oncol. 2021 Aug;15(8):2120-2139. doi: 10.1002/1878-0261.12897. Epub 2021 Feb 1. Mol Oncol. 2021. PMID: 33411958 Free PMC article.

7

Post-transcriptional regulation of BIRC5/survivin expression and induction of apoptosis in breast cancer cells by tristetraprolin.

Al-Yahya S, Al-Saif M, Al-Ghamdi M, Moghrabi W, Khabar KSA, Al-Souhibani N. Al-Yahya S, et al. RNA Biol. 2024 Jan;21(1):1-15. doi: 10.1080/15476286.2023.2286101. Epub 2023 Dec 18. RNA Biol. 2024. PMID: 38111129 Free PMC article.

8

Global analysis of the abundance of AU-rich mRNAs in response to glucocorticoid treatment.

Muazzen Z, Moghrabi W, Bakheet T, Mahmoud L, Al-Saif M, Khabar KSA, Hitti EG. Muazzen Z, et al. Sci Rep. 2024 Jan 9;14(1):913. doi: 10.1038/s41598-024-51301-6. Sci Rep. 2024. PMID: 38195703 Free PMC article.

9

Hydroxychloroquine attenuates double-stranded RNA-stimulated hyper-phosphorylation of tristetraprolin/ZFP36 and AU-rich mRNA stabilization.

Hitti EG, Muazzen Z, Moghrabi W, Al-Yahya S, Khabar KSA. Hitti EG, et al. Immunology. 2024 Nov;173(3):511-519. doi: 10.1111/imm.13835. Epub 2024 Jul 24. Immunology. 2024. PMID: 39046234

10

Sunitinib Stimulates Expression of VEGFC by Tumor Cells and Promotes Lymphangiogenesis in Clear Cell Renal Cell Carcinomas.

Dufies M, Giuliano S, Ambrosetti D, Claren A, Ndiaye PD, Mastri M, Moghrabi W, Cooley LS, Ettaiche M, Chamorey E, Parola J, Vial V, Lupu-Plesu M, Bernhard JC, Ravaud A, Borchiellini D, Ferrero JM, Bikfalvi A, Ebos JM, Khabar KS, Grépin R, Pagès G. Dufies M, et al. Cancer Res. 2017 Mar 1;77(5):1212-1226. doi: 10.1158/0008-5472.CAN-16-3088. Epub 2017 Jan 13. Cancer Res. 2017. PMID: 28087600

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