Wooldridge L - Search Results

1

Divergent roles for antigenic drive in the aetiology of primary versus dasatinib-associated CD8⁺ TCR-Vβ⁺ expansions.

Lissina A, McLaren JE, Ilander M, Andersson EI, Lewis CS, Clement M, Herman A, Ladell K, Llewellyn-Lacey S, Miners KL, Gostick E, Melenhorst JJ, Barrett AJ, Price DA, Mustjoki S, Wooldridge L. Lissina A, et al. Among authors: wooldridge l. Sci Rep. 2018 Feb 7;8(1):2534. doi: 10.1038/s41598-017-18062-x. Sci Rep. 2018. PMID: 29416058 Free PMC article.

2

The CD8 T cell coreceptor exhibits disproportionate biological activity at extremely low binding affinities.

Hutchinson SL, Wooldridge L, Tafuro S, Laugel B, Glick M, Boulter JM, Jakobsen BK, Price DA, Sewell AK. Hutchinson SL, et al. Among authors: wooldridge l. J Biol Chem. 2003 Jul 4;278(27):24285-93. doi: 10.1074/jbc.M300633200. Epub 2003 Apr 15. J Biol Chem. 2003. PMID: 12697765 Free article.

3

Anti-CD8 antibodies can inhibit or enhance peptide-MHC class I (pMHCI) multimer binding: this is paralleled by their effects on CTL activation and occurs in the absence of an interaction between pMHCI and CD8 on the cell surface.

Wooldridge L, Hutchinson SL, Choi EM, Lissina A, Jones E, Mirza F, Dunbar PR, Price DA, Cerundolo V, Sewell AK. Wooldridge L, et al. J Immunol. 2003 Dec 15;171(12):6650-60. doi: 10.4049/jimmunol.171.12.6650. J Immunol. 2003. PMID: 14662868

4

Interaction between the CD8 coreceptor and major histocompatibility complex class I stabilizes T cell receptor-antigen complexes at the cell surface.

Wooldridge L, van den Berg HA, Glick M, Gostick E, Laugel B, Hutchinson SL, Milicic A, Brenchley JM, Douek DC, Price DA, Sewell AK. Wooldridge L, et al. J Biol Chem. 2005 Jul 29;280(30):27491-501. doi: 10.1074/jbc.M500555200. Epub 2005 Apr 18. J Biol Chem. 2005. PMID: 15837791 Free PMC article.

5

Avidity for antigen shapes clonal dominance in CD8+ T cell populations specific for persistent DNA viruses.

Price DA, Brenchley JM, Ruff LE, Betts MR, Hill BJ, Roederer M, Koup RA, Migueles SA, Gostick E, Wooldridge L, Sewell AK, Connors M, Douek DC. Price DA, et al. Among authors: wooldridge l. J Exp Med. 2005 Nov 21;202(10):1349-61. doi: 10.1084/jem.20051357. Epub 2005 Nov 14. J Exp Med. 2005. PMID: 16287711 Free PMC article.

6

Anti-coreceptor antibodies profoundly affect staining with peptide-MHC class I and class II tetramers.

Wooldridge L, Scriba TJ, Milicic A, Laugel B, Gostick E, Price DA, Phillips RE, Sewell AK. Wooldridge L, et al. Eur J Immunol. 2006 Jul;36(7):1847-55. doi: 10.1002/eji.200635886. Eur J Immunol. 2006. PMID: 16783852 Free article.

7

Functional and biophysical characterization of an HLA-A*6801-restricted HIV-specific T cell receptor.

Gostick E, Cole DK, Hutchinson SL, Wooldridge L, Tafuro S, Laugel B, Lissina A, Oxenius A, Boulter JM, Price DA, Sewell AK. Gostick E, et al. Among authors: wooldridge l. Eur J Immunol. 2007 Feb;37(2):479-86. doi: 10.1002/eji.200636243. Eur J Immunol. 2007. PMID: 17273992 Free PMC article.

8

Enhanced immunogenicity of CTL antigens through mutation of the CD8 binding MHC class I invariant region.

Wooldridge L, Lissina A, Vernazza J, Gostick E, Laugel B, Hutchinson SL, Mirza F, Dunbar PR, Boulter JM, Glick M, Cerundolo V, van den Berg HA, Price DA, Sewell AK. Wooldridge L, et al. Eur J Immunol. 2007 May;37(5):1323-33. doi: 10.1002/eji.200636765. Eur J Immunol. 2007. PMID: 17429845 Free PMC article.

9

Different T cell receptor affinity thresholds and CD8 coreceptor dependence govern cytotoxic T lymphocyte activation and tetramer binding properties.

Laugel B, van den Berg HA, Gostick E, Cole DK, Wooldridge L, Boulter J, Milicic A, Price DA, Sewell AK. Laugel B, et al. Among authors: wooldridge l. J Biol Chem. 2007 Aug 17;282(33):23799-810. doi: 10.1074/jbc.M700976200. Epub 2007 May 31. J Biol Chem. 2007. PMID: 17540778 Free article.

10

Profound inhibition of antigen-specific T-cell effector functions by dasatinib.

Weichsel R, Dix C, Wooldridge L, Clement M, Fenton-May A, Sewell AK, Zezula J, Greiner E, Gostick E, Price DA, Einsele H, Seggewiss R. Weichsel R, et al. Among authors: wooldridge l. Clin Cancer Res. 2008 Apr 15;14(8):2484-91. doi: 10.1158/1078-0432.CCR-07-4393. Clin Cancer Res. 2008. PMID: 18413841 Free article.

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