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134 results

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Page 1
Recombinant methioninase (rMETase) is an effective therapeutic for BRAF-V600E-negative as well as -positive melanoma in patient-derived orthotopic xenograft (PDOX) mouse models.
Kawaguchi K, Igarashi K, Li S, Han Q, Tan Y, Miyake K, Kiyuna T, Miyake M, Murakami T, Chmielowski B, Nelson SD, Russell TA, Dry SM, Li Y, Unno M, Eilber FC, Hoffman RM. Kawaguchi K, et al. Among authors: chmielowski b. Oncotarget. 2017 Dec 12;9(1):915-923. doi: 10.18632/oncotarget.23185. eCollection 2018 Jan 2. Oncotarget. 2017. PMID: 29416666 Free PMC article.
Risk stratification of patients undergoing pulmonary metastasectomy for soft tissue and bone sarcomas.
Lin AY, Kotova S, Yanagawa J, Elbuluk O, Wang G, Kar N, Elashoff D, Grogan T, Cameron RB, Singh A, Chmielowski B, Federman N, Nelson SD, Lee P, Eilber FC, Lee JM. Lin AY, et al. Among authors: chmielowski b. J Thorac Cardiovasc Surg. 2015 Jan;149(1):85-92. doi: 10.1016/j.jtcvs.2014.09.039. Epub 2014 Sep 18. J Thorac Cardiovasc Surg. 2015. PMID: 25312228 Free article.
Characterizing the immune microenvironment of malignant peripheral nerve sheath tumor by PD-L1 expression and presence of CD8+ tumor infiltrating lymphocytes.
Shurell E, Singh AS, Crompton JG, Jensen S, Li Y, Dry S, Nelson S, Chmielowski B, Bernthal N, Federman N, Tumeh P, Eilber FC. Shurell E, et al. Among authors: chmielowski b. Oncotarget. 2016 Sep 27;7(39):64300-64308. doi: 10.18632/oncotarget.11734. Oncotarget. 2016. PMID: 27588404 Free PMC article.
Vemurafenib-resistant BRAF-V600E-mutated melanoma is regressed by MEK-targeting drug trametinib, but not cobimetinib in a patient-derived orthotopic xenograft (PDOX) mouse model.
Kawaguchi K, Murakami T, Chmielowski B, Igarashi K, Kiyuna T, Unno M, Nelson SD, Russell TA, Dry SM, Li Y, Eilber FC, Hoffman RM. Kawaguchi K, et al. Among authors: chmielowski b. Oncotarget. 2016 Nov 1;7(44):71737-71743. doi: 10.18632/oncotarget.12328. Oncotarget. 2016. PMID: 27690220 Free PMC article.
Tumor-targeting Salmonella typhimurium A1-R combined with temozolomide regresses malignant melanoma with a BRAF-V600E mutation in a patient-derived orthotopic xenograft (PDOX) model.
Kawaguchi K, Igarashi K, Murakami T, Chmielowski B, Kiyuna T, Zhao M, Zhang Y, Singh A, Unno M, Nelson SD, Russell TA, Dry SM, Li Y, Eilber FC, Hoffman RM. Kawaguchi K, et al. Among authors: chmielowski b. Oncotarget. 2016 Dec 27;7(52):85929-85936. doi: 10.18632/oncotarget.13231. Oncotarget. 2016. PMID: 27835903 Free PMC article.
Tumor-Targeting Salmonella typhimurium A1-R Sensitizes Melanoma With a BRAF-V600E Mutation to Vemurafenib in a Patient-Derived Orthotopic Xenograft (PDOX) Nude Mouse Model.
Kawaguchi K, Igarashi K, Murakami T, Zhao M, Zhang Y, Chmielowski B, Kiyuna T, Nelson SD, Russell TA, Dry SM, Li Y, Unno M, Eilber FC, Hoffman RM. Kawaguchi K, et al. Among authors: chmielowski b. J Cell Biochem. 2017 Aug;118(8):2314-2319. doi: 10.1002/jcb.25886. Epub 2017 Apr 25. J Cell Biochem. 2017. PMID: 28106277
Combination of gemcitabine and docetaxel regresses both gastric leiomyosarcoma proliferation and invasion in an imageable patient-derived orthotopic xenograft (iPDOX) model.
Kawaguchi K, Igarashi K, Murakami T, Kiyuna T, Nelson SD, Dry SM, Li Y, Russell TA, Singh AS, Chmielowski B, Unno M, Eilber FC, Hoffman RM. Kawaguchi K, et al. Among authors: chmielowski b. Cell Cycle. 2017 Jun 3;16(11):1063-1069. doi: 10.1080/15384101.2017.1314406. Epub 2017 Apr 20. Cell Cycle. 2017. PMID: 28426279 Free PMC article.
Salmonella typhimurium A1-R targeting of a chemotherapy-resistant BRAF-V600E melanoma in a patient-derived orthotopic xenograft (PDOX) model is enhanced in combination with either vemurafenib or temozolomide.
Kawaguchi K, Igarashi K, Murakami T, Kiyuna T, Zhao M, Zhang Y, Nelson SD, Russell TA, Dry SM, Singh AS, Chmielowski B, Li Y, Unno M, Eilber FC, Hoffman RM. Kawaguchi K, et al. Among authors: chmielowski b. Cell Cycle. 2017 Jul 3;16(13):1288-1294. doi: 10.1080/15384101.2017.1314420. Epub 2017 Jun 16. Cell Cycle. 2017. PMID: 28622068 Free PMC article.
134 results