Hoffman RM - Search Results

1

Recombinant methioninase (rMETase) is an effective therapeutic for BRAF-V600E-negative as well as -positive melanoma in patient-derived orthotopic xenograft (PDOX) mouse models.

Kawaguchi K, Igarashi K, Li S, Han Q, Tan Y, Miyake K, Kiyuna T, Miyake M, Murakami T, Chmielowski B, Nelson SD, Russell TA, Dry SM, Li Y, Unno M, Eilber FC, Hoffman RM. Kawaguchi K, et al. Among authors: hoffman rm. Oncotarget. 2017 Dec 12;9(1):915-923. doi: 10.18632/oncotarget.23185. eCollection 2018 Jan 2. Oncotarget. 2017. PMID: 29416666 Free PMC article.

2

IL-2 gene therapy of advanced lung cancer patients.

Tan Y, Xu M, Wang W, Zhang F, Li D, Xu X, Gu J, Hoffman RM. Tan Y, et al. Among authors: hoffman rm. Anticancer Res. 1996 Jul-Aug;16(4A):1993-8. Anticancer Res. 1996. PMID: 8712732 Clinical Trial.

3

Methionine depletion modulates the antitumor and antimetastatic efficacy of ethionine.

Guo H, Tan Y, Kubota T, Moossa AR, Hoffman RM. Guo H, et al. Among authors: hoffman rm. Anticancer Res. 1996 Sep-Oct;16(5A):2719-23. Anticancer Res. 1996. PMID: 8917377

4

Anticancer efficacy of methioninase in vivo.

Tan Y, Xu M, Guo H, Sun X, Kubota T, Hoffman RM. Tan Y, et al. Among authors: hoffman rm. Anticancer Res. 1996 Nov-Dec;16(6C):3931-6. Anticancer Res. 1996. PMID: 9042315

5

Serum methionine depletion without side effects by methioninase in metastatic breast cancer patients.

Tan Y, Zavala J Sr, Xu M, Zavala J Jr, Hoffman RM. Tan Y, et al. Among authors: hoffman rm. Anticancer Res. 1996 Nov-Dec;16(6C):3937-42. Anticancer Res. 1996. PMID: 9042316 Clinical Trial.

6

Overexpression and large-scale production of recombinant L-methionine-alpha-deamino-gamma-mercaptomethane-lyase for novel anticancer therapy.

Tan Y, Xu M, Tan X, Tan X, Wang X, Saikawa Y, Nagahama T, Sun X, Lenz M, Hoffman RM. Tan Y, et al. Among authors: hoffman rm. Protein Expr Purif. 1997 Mar;9(2):233-45. doi: 10.1006/prep.1996.0700. Protein Expr Purif. 1997. PMID: 9056489

7

Recombinant methioninase infusion reduces the biochemical endpoint of serum methionine with minimal toxicity in high-stage cancer patients.

Tan Y, Zavala J Sr, Han Q, Xu M, Sun X, Tan X, Tan X, Magana R, Geller J, Hoffman RM. Tan Y, et al. Among authors: hoffman rm. Anticancer Res. 1997 Sep-Oct;17(5B):3857-60. Anticancer Res. 1997. PMID: 9427792 Clinical Trial.

8

Polyethylene glycol conjugation of recombinant methioninase for cancer therapy.

Tan Y, Sun X, Xu M, An Z, Tan X, Han Q, Miljkovic DA, Yang M, Hoffman RM. Tan Y, et al. Among authors: hoffman rm. Protein Expr Purif. 1998 Feb;12(1):45-52. doi: 10.1006/prep.1997.0805. Protein Expr Purif. 1998. PMID: 9473456

9

High expression, purification, and properties of recombinant homocysteine alpha, gamma-lyase.

Han Q, Lenz M, Tan Y, Xu M, Sun X, Tan X, Tan X, Tang L, Miljkovic D, Hoffman RM. Han Q, et al. Among authors: hoffman rm. Protein Expr Purif. 1998 Nov;14(2):267-74. doi: 10.1006/prep.1998.0955. Protein Expr Purif. 1998. PMID: 9790890

10

Efficacy of recombinant methioninase in combination with cisplatin on human colon tumors in nude mice.

Tan Y, Sun X, Xu M, Tan X, Sasson A, Rashidi B, Han Q, Tan X, Wang X, An Z, Sun FX, Hoffman RM. Tan Y, et al. Among authors: hoffman rm. Clin Cancer Res. 1999 Aug;5(8):2157-63. Clin Cancer Res. 1999. PMID: 10473100

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