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A secondary RET mutation in the activation loop conferring resistance to vandetanib.
Nakaoku T, Kohno T, Araki M, Niho S, Chauhan R, Knowles PP, Tsuchihara K, Matsumoto S, Shimada Y, Mimaki S, Ishii G, Ichikawa H, Nagatoishi S, Tsumoto K, Okuno Y, Yoh K, McDonald NQ, Goto K. Nakaoku T, et al. Among authors: ichikawa h. Nat Commun. 2018 Feb 12;9(1):625. doi: 10.1038/s41467-018-02994-7. Nat Commun. 2018. PMID: 29434222 Free PMC article.
KIF5B-RET fusions in lung adenocarcinoma.
Kohno T, Ichikawa H, Totoki Y, Yasuda K, Hiramoto M, Nammo T, Sakamoto H, Tsuta K, Furuta K, Shimada Y, Iwakawa R, Ogiwara H, Oike T, Enari M, Schetter AJ, Okayama H, Haugen A, Skaug V, Chiku S, Yamanaka I, Arai Y, Watanabe S, Sekine I, Ogawa S, Harris CC, Tsuda H, Yoshida T, Yokota J, Shibata T. Kohno T, et al. Among authors: ichikawa h. Nat Med. 2012 Feb 12;18(3):375-7. doi: 10.1038/nm.2644. Nat Med. 2012. PMID: 22327624 Free PMC article.
Molecular mechanisms underlying oncogenic RET fusion in lung adenocarcinoma.
Mizukami T, Shiraishi K, Shimada Y, Ogiwara H, Tsuta K, Ichikawa H, Sakamoto H, Kato M, Shibata T, Nakano T, Kohno T. Mizukami T, et al. Among authors: ichikawa h. J Thorac Oncol. 2014 May;9(5):622-30. doi: 10.1097/JTO.0000000000000135. J Thorac Oncol. 2014. PMID: 24722152 Free article.
TSPAN2 is involved in cell invasion and motility during lung cancer progression.
Otsubo C, Otomo R, Miyazaki M, Matsushima-Hibiya Y, Kohno T, Iwakawa R, Takeshita F, Okayama H, Ichikawa H, Saya H, Kiyono T, Ochiya T, Tashiro F, Nakagama H, Yokota J, Enari M. Otsubo C, et al. Among authors: ichikawa h. Cell Rep. 2014 Apr 24;7(2):527-538. doi: 10.1016/j.celrep.2014.03.027. Epub 2014 Apr 13. Cell Rep. 2014. PMID: 24726368 Free article.
Druggable oncogene fusions in invasive mucinous lung adenocarcinoma.
Nakaoku T, Tsuta K, Ichikawa H, Shiraishi K, Sakamoto H, Enari M, Furuta K, Shimada Y, Ogiwara H, Watanabe S, Nokihara H, Yasuda K, Hiramoto M, Nammo T, Ishigame T, Schetter AJ, Okayama H, Harris CC, Kim YH, Mishima M, Yokota J, Yoshida T, Kohno T. Nakaoku T, et al. Among authors: ichikawa h. Clin Cancer Res. 2014 Jun 15;20(12):3087-93. doi: 10.1158/1078-0432.CCR-14-0107. Epub 2014 Apr 11. Clin Cancer Res. 2014. PMID: 24727320 Free PMC article.
TSPAN12 is a critical factor for cancer-fibroblast cell contact-mediated cancer invasion.
Otomo R, Otsubo C, Matsushima-Hibiya Y, Miyazaki M, Tashiro F, Ichikawa H, Kohno T, Ochiya T, Yokota J, Nakagama H, Taya Y, Enari M. Otomo R, et al. Among authors: ichikawa h. Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18691-6. doi: 10.1073/pnas.1412062112. Epub 2014 Dec 15. Proc Natl Acad Sci U S A. 2014. PMID: 25512506 Free PMC article.
Development of lung adenocarcinomas with exclusive dependence on oncogene fusions.
Saito M, Shimada Y, Shiraishi K, Sakamoto H, Tsuta K, Totsuka H, Chiku S, Ichikawa H, Kato M, Watanabe S, Yoshida T, Yokota J, Kohno T. Saito M, et al. Among authors: ichikawa h. Cancer Res. 2015 Jun 1;75(11):2264-71. doi: 10.1158/0008-5472.CAN-14-3282. Epub 2015 Apr 8. Cancer Res. 2015. PMID: 25855381
Picoliter-Droplet Digital Polymerase Chain Reaction-Based Analysis of Cell-Free Plasma DNA to Assess EGFR Mutations in Lung Adenocarcinoma That Confer Resistance to Tyrosine-Kinase Inhibitors.
Seki Y, Fujiwara Y, Kohno T, Takai E, Sunami K, Goto Y, Horinouchi H, Kanda S, Nokihara H, Watanabe S, Ichikawa H, Yamamoto N, Kuwano K, Ohe Y. Seki Y, et al. Among authors: ichikawa h. Oncologist. 2016 Feb;21(2):156-64. doi: 10.1634/theoncologist.2015-0288. Epub 2016 Jan 14. Oncologist. 2016. PMID: 26768482 Free PMC article.
1,934 results