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IL-27: a double agent in the IL-6 family.
Jones GW, Hill DG, Cardus A, Jones SA. Jones GW, et al. Among authors: hill dg. Clin Exp Immunol. 2018 Jul;193(1):37-46. doi: 10.1111/cei.13116. Epub 2018 Mar 9. Clin Exp Immunol. 2018. PMID: 29437229 Free PMC article. Review.
In Vivo Models for Inflammatory Arthritis.
Jones GW, Hill DG, Sime K, Williams AS. Jones GW, et al. Among authors: hill dg. Methods Mol Biol. 2018;1725:101-118. doi: 10.1007/978-1-4939-7568-6_9. Methods Mol Biol. 2018. PMID: 29322412
Activation of naïve CD4+ T cells re-tunes STAT1 signaling to deliver unique cytokine responses in memory CD4+ T cells.
Twohig JP, Cardus Figueras A, Andrews R, Wiede F, Cossins BC, Derrac Soria A, Lewis MJ, Townsend MJ, Millrine D, Li J, Hill DG, Uceda Fernandez J, Liu X, Szomolay B, Pepper CJ, Taylor PR, Pitzalis C, Tiganis T, Williams NM, Jones GW, Jones SA. Twohig JP, et al. Among authors: hill dg. Nat Immunol. 2019 Apr;20(4):458-470. doi: 10.1038/s41590-019-0350-0. Epub 2019 Mar 19. Nat Immunol. 2019. PMID: 30890796 Free PMC article.
Impaired Interleukin-27-Mediated Control of CD4+ T Cell Function Impact on Ectopic Lymphoid Structure Formation in Patients With Sjögren's Syndrome.
Lucchesi D, Coleby R, Pontarini E, Prediletto E, Rivellese F, Hill DG, Derrac Soria A, Jones SA, Humphreys IR, Sutcliffe N, Tappuni AR, Pitzalis C, Jones GW, Bombardieri M. Lucchesi D, et al. Among authors: hill dg. Arthritis Rheumatol. 2020 Sep;72(9):1559-1570. doi: 10.1002/art.41289. Epub 2020 Jul 21. Arthritis Rheumatol. 2020. PMID: 32307922
Canagliflozin impairs T cell effector function via metabolic suppression in autoimmunity.
Jenkins BJ, Blagih J, Ponce-Garcia FM, Canavan M, Gudgeon N, Eastham S, Hill D, Hanlon MM, Ma EH, Bishop EL, Rees A, Cronin JG, Jury EC, Dimeloe SK, Veale DJ, Thornton CA, Vousden KH, Finlay DK, Fearon U, Jones GW, Sinclair LV, Vincent EE, Jones N. Jenkins BJ, et al. Cell Metab. 2023 Jul 11;35(7):1132-1146.e9. doi: 10.1016/j.cmet.2023.05.001. Epub 2023 May 24. Cell Metab. 2023. PMID: 37230079 Free article.
IL-27 maintains cytotoxic Ly6C+ γδ T cells that arise from immature precursors.
Wiesheu R, Edwards SC, Hedley A, Hall H, Tosolini M, Fares da Silva MGF, Sumaria N, Castenmiller SM, Wardak L, Optaczy Y, Lynn A, Hill DG, Hayes AJ, Hay J, Kilbey A, Shaw R, Whyte D, Walsh PJ, Michie AM, Graham GJ, Manoharan A, Halsey C, Blyth K, Wolkers MC, Miller C, Pennington DJ, Jones GW, Fournie JJ, Bekiaris V, Coffelt SB. Wiesheu R, et al. Among authors: hill dg. EMBO J. 2024 Jul;43(14):2878-2907. doi: 10.1038/s44318-024-00133-1. Epub 2024 May 30. EMBO J. 2024. PMID: 38816652 Free PMC article.
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