Meanwell NA - Search Results

1

Discovery of morpholine-based aryl sulfonamides as Na_v1.7 inhibitors.

Wu YJ, Guernon J, McClure A, Venables B, Rajamani R, Robbins KJ, Knox RJ, Matchett M, Pieschl RL, Herrington J, Bristow LJ, Meanwell NA, Olson R, Thompson LA, Dzierba C. Wu YJ, et al. Among authors: meanwell na. Bioorg Med Chem Lett. 2018 Mar 1;28(5):958-962. doi: 10.1016/j.bmcl.2018.01.035. Epub 2018 Feb 1. Bioorg Med Chem Lett. 2018. PMID: 29439904

2

Inhibitors of blood platelet cAMP phosphodiesterase. 2. Structure-activity relationships associated with 1,3-dihydro-2H-imidazo[4,5-b]quinolin-2-ones substituted with functionalized side chains.

Meanwell NA, Pearce BC, Roth HR, Smith EC, Wedding DL, Wright JJ, Buchanan JO, Baryla UM, Gamberdella M, Gillespie E, et al. Meanwell NA, et al. J Med Chem. 1992 Jul 10;35(14):2672-87. doi: 10.1021/jm00092a019. J Med Chem. 1992. PMID: 1321910

3

Inhibitors of blood platelet cAMP phosphodiesterase. 3. 1,3-Dihydro-2H-imidazo[4,5-b]quinolin-2-one derivatives with enhanced aqueous solubility.

Meanwell NA, Dennis RD, Roth HR, Rosenfeld MJ, Smith EC, Wright JJ, Buchanan JO, Brassard CL, Gamberdella M, Gillespie E, et al. Meanwell NA, et al. J Med Chem. 1992 Jul 10;35(14):2688-96. doi: 10.1021/jm00092a020. J Med Chem. 1992. PMID: 1321911

4

Structure-activity relationships associated with 3,4,5-triphenyl-1H-pyrazole-1-nonanoic acid, a nonprostanoid prostacyclin mimetic.

Meanwell NA, Rosenfeld MJ, Wright JJ, Brassard CL, Buchanan JO, Federici ME, Fleming JS, Seiler SM. Meanwell NA, et al. J Med Chem. 1992 Jan 24;35(2):389-97. doi: 10.1021/jm00080a028. J Med Chem. 1992. PMID: 1370696

5

Nonprostanoid prostacyclin mimetics. 2. 4,5-Diphenyloxazole derivatives.

Meanwell NA, Rosenfeld MJ, Trehan AK, Wright JJ, Brassard CL, Buchanan JO, Federici ME, Fleming JS, Gamberdella M, Zavoico GB, et al. Meanwell NA, et al. J Med Chem. 1992 Sep 18;35(19):3483-97. doi: 10.1021/jm00097a006. J Med Chem. 1992. PMID: 1404230

6

Nonprostanoid prostacyclin mimetics. 3. Structural variations of the diphenyl heterocycle moiety.

Meanwell NA, Rosenfeld MJ, Trehan AK, Romine JL, Wright JJ, Brassard CL, Buchanan JO, Federici ME, Fleming JS, Gamberdella M, et al. Meanwell NA, et al. J Med Chem. 1992 Sep 18;35(19):3498-512. doi: 10.1021/jm00097a007. J Med Chem. 1992. PMID: 1404231

7

Nonprostanoid prostacyclin mimetics. 5. Structure-activity relationships associated with [3-[4-(4,5-diphenyl-2-oxazolyl)-5- oxazolyl]phenoxy]acetic acid.

Meanwell NA, Romine JL, Rosenfeld MJ, Martin SW, Trehan AK, Wright JJ, Malley MF, Gougoutas JZ, Brassard CL, Buchanan JO, et al. Meanwell NA, et al. J Med Chem. 1993 Nov 26;36(24):3884-903. doi: 10.1021/jm00076a018. J Med Chem. 1993. PMID: 7504734

8

Azetidin-2-one derivatives as inhibitors of thrombin.

Han WT, Trehan AK, Wright JJ, Federici ME, Seiler SM, Meanwell NA. Han WT, et al. Among authors: meanwell na. Bioorg Med Chem. 1995 Aug;3(8):1123-43. doi: 10.1016/0968-0896(95)00101-l. Bioorg Med Chem. 1995. PMID: 7582985

9

Active site-directed thrombin inhibitors--II. Studies related to arginine/guanidine bioisosteres.

St Laurent DR, Balasubramanian N, Han WT, Trehan A, Federici ME, Meanwell NA, Wright JJ, Seiler SM. St Laurent DR, et al. Among authors: meanwell na. Bioorg Med Chem. 1995 Aug;3(8):1145-56. doi: 10.1016/0968-0896(95)00103-n. Bioorg Med Chem. 1995. PMID: 7582986

10

Inhibitors of blood platelet cAMP phosphodiesterase. 4. Structural variation of the side-chain terminus of water-soluble 1,3-dihydro-2H-imidazo[4,5-b]quinolin-2-one derivatives.

Meanwell NA, Hewawasam P, Thomas JA, Wright JJ, Russell JW, Gamberdella M, Goldenberg HJ, Seiler SM, Zavoico GB. Meanwell NA, et al. J Med Chem. 1993 Oct 29;36(22):3251-64. doi: 10.1021/jm00074a005. J Med Chem. 1993. PMID: 8230115

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