Inoue SI - Search Results

1

In Vitro and In Vivo Activities of DS-2969b, a Novel GyrB Inhibitor, against Clostridium difficile.

Mathur T, Barman TK, Kumar M, Singh D, Kumar R, Khera MK, Yamada M, Inoue SI, Upadhyay DJ, Masuda N. Mathur T, et al. Among authors: inoue si. Antimicrob Agents Chemother. 2018 Mar 27;62(4):e02157-17. doi: 10.1128/AAC.02157-17. Print 2018 Apr. Antimicrob Agents Chemother. 2018. PMID: 29439962 Free PMC article.

2

Pharmacokinetics, distribution, and disposition of esaxerenone, a novel, highly potent and selective non-steroidal mineralocorticoid receptor antagonist, in rats and monkeys.

Yamada M, Takei M, Suzuki E, Takakusa H, Kotsuma M, Washio T, Murayama N, Inoue SI, Izumi T. Yamada M, et al. Among authors: inoue si. Xenobiotica. 2017 Dec;47(12):1090-1103. doi: 10.1080/00498254.2016.1263766. Epub 2016 Dec 12. Xenobiotica. 2017. PMID: 27866463

3

Effect of DS-2969b, a novel GyrB inhibitor, on rat and monkey intestinal microbiota.

Kumar M, Mathur T, Joshi V, Upadhyay DJ, Inoue SI, Masuda N. Kumar M, et al. Among authors: inoue si. Anaerobe. 2018 Jun;51:120-123. doi: 10.1016/j.anaerobe.2018.04.017. Epub 2018 May 2. Anaerobe. 2018. PMID: 29758524

4

Critical Impact of Drug-Drug Interactions via Intestinal CYP3A in the Risk Assessment of Weak Perpetrators Using Physiologically Based Pharmacokinetic Models.

Yamada M, Inoue SI, Sugiyama D, Nishiya Y, Ishizuka T, Watanabe A, Watanabe K, Yamashita S, Watanabe N. Yamada M, et al. Among authors: inoue si. Drug Metab Dispos. 2020 Apr;48(4):288-296. doi: 10.1124/dmd.119.089599. Epub 2020 Jan 29. Drug Metab Dispos. 2020. PMID: 31996361

5

Drug-Drug Interaction Risk Assessment of Esaxerenone as a Perpetrator by In Vitro Studies and Static and Physiologically Based Pharmacokinetic Models.

Yamada M, Ishizuka T, Inoue SI, Rozehnal V, Fischer T, Sugiyama D. Yamada M, et al. Among authors: inoue si. Drug Metab Dispos. 2020 Sep;48(9):769-777. doi: 10.1124/dmd.120.090928. Epub 2020 Jul 2. Drug Metab Dispos. 2020. PMID: 32616542

6

Preclinical pharmacology profile of CS-706, a novel cyclooxygenase-2 selective inhibitor, with potent antinociceptive and anti-inflammatory effects.

Ushiyama S, Yamada T, Murakami Y, Kumakura S, Inoue S, Suzuki K, Nakao A, Kawara A, Kimura T. Ushiyama S, et al. Eur J Pharmacol. 2008 Jan 6;578(1):76-86. doi: 10.1016/j.ejphar.2007.08.034. Epub 2007 Sep 11. Eur J Pharmacol. 2008. PMID: 17920584

7

Lead optimization of 5-amino-6-(2,2-dimethyl-5-oxo-4-phenylpiperazin-1-yl)-4-hydroxyhexanamides to reduce a cardiac safety issue: discovery of DS-8108b, an orally active renin inhibitor.

Nakamura Y, Fujimoto T, Ogawa Y, Namiki H, Suzuki S, Asano M, Sugita C, Mochizuki A, Miyazaki S, Tamaki K, Nagai Y, Inoue S, Nagayama T, Kato M, Chiba K, Takasuna K, Nishi T. Nakamura Y, et al. Bioorg Med Chem. 2013 Jun 1;21(11):3175-96. doi: 10.1016/j.bmc.2013.03.022. Epub 2013 Mar 26. Bioorg Med Chem. 2013. PMID: 23598247

8

Identification of a novel hormone sensitive lipase inhibitor with a reduced potential of reactive metabolites formation.

Ogiyama T, Yamaguchi M, Kurikawa N, Honzumi S, Yamamoto Y, Sugiyama D, Takakusa H, Inoue SI. Ogiyama T, et al. Among authors: inoue si. Bioorg Med Chem. 2017 Apr 1;25(7):2234-2243. doi: 10.1016/j.bmc.2017.02.045. Epub 2017 Feb 27. Bioorg Med Chem. 2017. PMID: 28279560

9

CS-706, a novel cyclooxygenase-2 selective inhibitor, prolonged the survival of tumor-bearing mice when treated alone or in combination with anti-tumor chemotherapeutic agents.

Senzaki M, Ishida S, Yada A, Hanai M, Fujiwara K, Inoue S, Kimura T, Kurakata S. Senzaki M, et al. Int J Cancer. 2008 Mar 15;122(6):1384-90. doi: 10.1002/ijc.23250. Int J Cancer. 2008. PMID: 18027868

10

Identification of a novel boronic acid as a potent, selective, and orally active hormone sensitive lipase inhibitor.

Ogiyama T, Yamaguchi M, Kurikawa N, Honzumi S, Yamamoto Y, Sugiyama D, Inoue S. Ogiyama T, et al. Bioorg Med Chem. 2016 Aug 15;24(16):3801-7. doi: 10.1016/j.bmc.2016.06.022. Epub 2016 Jun 11. Bioorg Med Chem. 2016. PMID: 27338659

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

128 results

Search Page

Filters