Pfeifer K - Search Results

1

Conditional ablation and conditional rescue models for Casq2 elucidate the role of development and of cell-type specific expression of Casq2 in the CPVT2 phenotype.

Flores DJ, Duong T, Brandenberger LO, Mitra A, Shirali A, Johnson JC, Springer D, Noguchi A, Yu ZX, Ebert SN, Ludwig A, Knollmann BC, Levin MD, Pfeifer K. Flores DJ, et al. Among authors: pfeifer k. Hum Mol Genet. 2018 May 1;27(9):1533-1544. doi: 10.1093/hmg/ddy060. Hum Mol Genet. 2018. PMID: 29452352 Free PMC article.

2

Targeted disruption of the Kcnq1 gene produces a mouse model of Jervell and Lange-Nielsen Syndrome.

Casimiro MC, Knollmann BC, Ebert SN, Vary JC Jr, Greene AE, Franz MR, Grinberg A, Huang SP, Pfeifer K. Casimiro MC, et al. Among authors: pfeifer k. Proc Natl Acad Sci U S A. 2001 Feb 27;98(5):2526-31. doi: 10.1073/pnas.041398998. Proc Natl Acad Sci U S A. 2001. PMID: 11226272 Free PMC article.

3

Nicotine induces a long QT phenotype in Kcnq1-deficient mouse hearts.

Tosaka T, Casimiro MC, Rong Q, Tella S, Oh M, Katchman AN, Pezzullo JC, Pfeifer K, Ebert SN. Tosaka T, et al. Among authors: pfeifer k. J Pharmacol Exp Ther. 2003 Sep;306(3):980-7. doi: 10.1124/jpet.103.053017. Epub 2003 May 23. J Pharmacol Exp Ther. 2003. PMID: 12766260

4

Isoproterenol exacerbates a long QT phenotype in Kcnq1-deficient neonatal mice: possible roles for human-like Kcnq1 isoform 1 and slow delayed rectifier K+ current.

Knollmann BC, Casimiro MC, Katchman AN, Sirenko SG, Schober T, Rong Q, Pfeifer K, Ebert SN. Knollmann BC, et al. Among authors: pfeifer k. J Pharmacol Exp Ther. 2004 Jul;310(1):311-8. doi: 10.1124/jpet.103.063743. Epub 2004 Mar 5. J Pharmacol Exp Ther. 2004. PMID: 15004216

5

Generating mouse models for studying the function and fate of intrinsic cardiac adrenergic cells.

Pfeifer K, Boe SP, Rong Q, Ebert SN. Pfeifer K, et al. Ann N Y Acad Sci. 2004 Jun;1018:418-23. doi: 10.1196/annals.1296.051. Ann N Y Acad Sci. 2004. PMID: 15240397

6

Targeted point mutagenesis of mouse Kcnq1: phenotypic analysis of mice with point mutations that cause Romano-Ward syndrome in humans.

Casimiro MC, Knollmann BC, Yamoah EN, Nie L, Vary JC Jr, Sirenko SG, Greene AE, Grinberg A, Huang SP, Ebert SN, Pfeifer K. Casimiro MC, et al. Among authors: pfeifer k. Genomics. 2004 Sep;84(3):555-64. doi: 10.1016/j.ygeno.2004.06.007. Genomics. 2004. PMID: 15498462

7

Targeted insertion of the Cre-recombinase gene at the phenylethanolamine n-methyltransferase locus: a new model for studying the developmental distribution of adrenergic cells.

Ebert SN, Rong Q, Boe S, Thompson RP, Grinberg A, Pfeifer K. Ebert SN, et al. Among authors: pfeifer k. Dev Dyn. 2004 Dec;231(4):849-58. doi: 10.1002/dvdy.20188. Dev Dyn. 2004. PMID: 15517585 Free article.

8

Casq2 deletion causes sarcoplasmic reticulum volume increase, premature Ca2+ release, and catecholaminergic polymorphic ventricular tachycardia.

Knollmann BC, Chopra N, Hlaing T, Akin B, Yang T, Ettensohn K, Knollmann BE, Horton KD, Weissman NJ, Holinstat I, Zhang W, Roden DM, Jones LR, Franzini-Armstrong C, Pfeifer K. Knollmann BC, et al. Among authors: pfeifer k. J Clin Invest. 2006 Sep;116(9):2510-20. doi: 10.1172/JCI29128. Epub 2006 Aug 24. J Clin Invest. 2006. PMID: 16932808 Free PMC article.

9

Kcnq1 contributes to an adrenergic-sensitive steady-state K+ current in mouse heart.

Knollmann BC, Sirenko S, Rong Q, Katchman AN, Casimiro M, Pfeifer K, Ebert SN. Knollmann BC, et al. Among authors: pfeifer k. Biochem Biophys Res Commun. 2007 Aug 17;360(1):212-8. doi: 10.1016/j.bbrc.2007.06.038. Epub 2007 Jun 15. Biochem Biophys Res Commun. 2007. PMID: 17597584 Free PMC article.

10

Modest reductions of cardiac calsequestrin increase sarcoplasmic reticulum Ca2+ leak independent of luminal Ca2+ and trigger ventricular arrhythmias in mice.

Chopra N, Kannankeril PJ, Yang T, Hlaing T, Holinstat I, Ettensohn K, Pfeifer K, Akin B, Jones LR, Franzini-Armstrong C, Knollmann BC. Chopra N, et al. Among authors: pfeifer k. Circ Res. 2007 Sep 14;101(6):617-26. doi: 10.1161/CIRCRESAHA.107.157552. Epub 2007 Jul 26. Circ Res. 2007. PMID: 17656677

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