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Rescue of Fragile X Syndrome Neurons by DNA Methylation Editing of the FMR1 Gene.
Liu XS, Wu H, Krzisch M, Wu X, Graef J, Muffat J, Hnisz D, Li CH, Yuan B, Xu C, Li Y, Vershkov D, Cacace A, Young RA, Jaenisch R. Liu XS, et al. Among authors: hnisz d. Cell. 2018 Feb 22;172(5):979-992.e6. doi: 10.1016/j.cell.2018.01.012. Epub 2018 Feb 15. Cell. 2018. PMID: 29456084 Free PMC article.
Super-enhancers in the control of cell identity and disease.
Hnisz D, Abraham BJ, Lee TI, Lau A, Saint-André V, Sigova AA, Hoke HA, Young RA. Hnisz D, et al. Cell. 2013 Nov 7;155(4):934-47. doi: 10.1016/j.cell.2013.09.053. Epub 2013 Oct 10. Cell. 2013. PMID: 24119843 Free PMC article.
3D Chromosome Regulatory Landscape of Human Pluripotent Cells.
Ji X, Dadon DB, Powell BE, Fan ZP, Borges-Rivera D, Shachar S, Weintraub AS, Hnisz D, Pegoraro G, Lee TI, Misteli T, Jaenisch R, Young RA. Ji X, et al. Among authors: hnisz d. Cell Stem Cell. 2016 Feb 4;18(2):262-75. doi: 10.1016/j.stem.2015.11.007. Epub 2015 Dec 10. Cell Stem Cell. 2016. PMID: 26686465 Free PMC article.
Activation of proto-oncogenes by disruption of chromosome neighborhoods.
Hnisz D, Weintraub AS, Day DS, Valton AL, Bak RO, Li CH, Goldmann J, Lajoie BR, Fan ZP, Sigova AA, Reddy J, Borges-Rivera D, Lee TI, Jaenisch R, Porteus MH, Dekker J, Young RA. Hnisz D, et al. Science. 2016 Mar 25;351(6280):1454-1458. doi: 10.1126/science.aad9024. Epub 2016 Mar 3. Science. 2016. PMID: 26940867 Free PMC article.
Small genomic insertions form enhancers that misregulate oncogenes.
Abraham BJ, Hnisz D, Weintraub AS, Kwiatkowski N, Li CH, Li Z, Weichert-Leahey N, Rahman S, Liu Y, Etchin J, Li B, Shen S, Lee TI, Zhang J, Look AT, Mansour MR, Young RA. Abraham BJ, et al. Among authors: hnisz d. Nat Commun. 2017 Feb 9;8:14385. doi: 10.1038/ncomms14385. Nat Commun. 2017. PMID: 28181482 Free PMC article.
Transcriptional Addiction in Cancer.
Bradner JE, Hnisz D, Young RA. Bradner JE, et al. Among authors: hnisz d. Cell. 2017 Feb 9;168(4):629-643. doi: 10.1016/j.cell.2016.12.013. Cell. 2017. PMID: 28187285 Free PMC article. Review.
37 results