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Page 1
A Series of 2-((1-Phenyl-1H-imidazol-5-yl)methyl)-1H-indoles as Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors.
Zheng Y, Stafford PM, Stover KR, Mohan DC, Gupta M, Keske EC, Schiavini P, Villar L, Wu F, Kreft A, Thomas K, Raaphorst E, Pasangulapati JP, Alla SR, Sharma S, Mittapalli RR, Sagamanova I, Johnson SL, Reed MA, Weaver DF. Zheng Y, et al. Among authors: schiavini p. ChemMedChem. 2021 Jul 20;16(14):2195-2205. doi: 10.1002/cmdc.202100107. Epub 2021 May 26. ChemMedChem. 2021. PMID: 33759400
3-Oxo-hexahydro-1H-isoindole-4-carboxylic Acid as a Drug Chiral Bicyclic Scaffold: Structure-Based Design and Preparation of Conformationally Constrained Covalent and Noncovalent Prolyl Oligopeptidase Inhibitors.
Mariaule G, De Cesco S, Airaghi F, Kurian J, Schiavini P, Rocheleau S, Huskić I, Auclair K, Mittermaier A, Moitessier N. Mariaule G, et al. Among authors: schiavini p. J Med Chem. 2016 May 12;59(9):4221-34. doi: 10.1021/acs.jmedchem.5b01296. Epub 2015 Dec 14. J Med Chem. 2016. PMID: 26619267
Discovery of novel small-molecule antagonists for GluK2.
Schiavini P, Dawe GB, Bowie D, Moitessier N. Schiavini P, et al. Bioorg Med Chem Lett. 2015 Jun 1;25(11):2416-20. doi: 10.1016/j.bmcl.2015.04.008. Epub 2015 Apr 10. Bioorg Med Chem Lett. 2015. PMID: 25913117
Ex vivo drug testing of patient-derived lung organoids to predict treatment responses for personalized medicine.
Taverna JA, Hung CN, Williams M, Williams R, Chen M, Kamali S, Sambandam V, Hsiang-Ling Chiu C, Osmulski PA, Gaczynska ME, DeArmond DT, Gaspard C, Mancini M, Kusi M, Pandya AN, Song L, Jin L, Schiavini P, Chen CL. Taverna JA, et al. Among authors: schiavini p. Lung Cancer. 2024 Apr;190:107533. doi: 10.1016/j.lungcan.2024.107533. Epub 2024 Mar 14. Lung Cancer. 2024. PMID: 38520909 Review.