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Small-Molecule Screen Identifies De Novo Nucleotide Synthesis as a Vulnerability of Cells Lacking SIRT3.
Gonzalez Herrera KN, Zaganjor E, Ishikawa Y, Spinelli JB, Yoon H, Lin JR, Satterstrom FK, Ringel A, Mulei S, Souza A, Gorham JM, Benson CC, Seidman JG, Sorger PK, Clish CB, Haigis MC. Gonzalez Herrera KN, et al. Among authors: zaganjor e. Cell Rep. 2018 Feb 20;22(8):1945-1955. doi: 10.1016/j.celrep.2018.01.076. Cell Rep. 2018. PMID: 29466723 Free PMC article.
Mitochondria and Cancer.
Vyas S, Zaganjor E, Haigis MC. Vyas S, et al. Among authors: zaganjor e. Cell. 2016 Jul 28;166(3):555-566. doi: 10.1016/j.cell.2016.07.002. Cell. 2016. PMID: 27471965 Free PMC article. Review.
PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2.
German NJ, Yoon H, Yusuf RZ, Murphy JP, Finley LW, Laurent G, Haas W, Satterstrom FK, Guarnerio J, Zaganjor E, Santos D, Pandolfi PP, Beck AH, Gygi SP, Scadden DT, Kaelin WG Jr, Haigis MC. German NJ, et al. Among authors: zaganjor e. Mol Cell. 2016 Sep 15;63(6):1006-20. doi: 10.1016/j.molcel.2016.08.014. Mol Cell. 2016. PMID: 27635760 Free PMC article.
SIRT4 Is a Regulator of Insulin Secretion.
Zaganjor E, Vyas S, Haigis MC. Zaganjor E, et al. Cell Chem Biol. 2017 Jun 22;24(6):656-658. doi: 10.1016/j.chembiol.2017.06.002. Cell Chem Biol. 2017. PMID: 28644956 Free article.
Mitochondrial efficiency directs cell fate.
Spinelli JB, Zaganjor E. Spinelli JB, et al. Among authors: zaganjor e. Nat Cell Biol. 2022 Feb;24(2):125-126. doi: 10.1038/s41556-021-00834-3. Nat Cell Biol. 2022. PMID: 35165414 No abstract available.
Inhibition of epithelial cell migration and Src/FAK signaling by SIRT3.
Lee JJ, van de Ven RAH, Zaganjor E, Ng MR, Barakat A, Demmers JJPG, Finley LWS, Gonzalez Herrera KN, Hung YP, Harris IS, Jeong SM, Danuser G, McAllister SS, Haigis MC. Lee JJ, et al. Among authors: zaganjor e. Proc Natl Acad Sci U S A. 2018 Jul 3;115(27):7057-7062. doi: 10.1073/pnas.1800440115. Epub 2018 Jun 18. Proc Natl Acad Sci U S A. 2018. PMID: 29915029 Free PMC article.
PHD3 Loss Promotes Exercise Capacity and Fat Oxidation in Skeletal Muscle.
Yoon H, Spinelli JB, Zaganjor E, Wong SJ, German NJ, Randall EC, Dean A, Clermont A, Paulo JA, Garcia D, Li H, Rombold O, Agar NYR, Goodyear LJ, Shaw RJ, Gygi SP, Auwerx J, Haigis MC. Yoon H, et al. Among authors: zaganjor e. Cell Metab. 2020 Aug 4;32(2):215-228.e7. doi: 10.1016/j.cmet.2020.06.017. Epub 2020 Jul 13. Cell Metab. 2020. PMID: 32663458 Free PMC article.
39 results