Endicott JA - Search Results

1

Identification of a novel ligand for the ATAD2 bromodomain with selectivity over BRD4 through a fragment growing approach.

Miller DC, Martin MP, Adhikari S, Brennan A, Endicott JA, Golding BT, Hardcastle IR, Heptinstall A, Hobson S, Jennings C, Molyneux L, Ng Y, Wedge SR, Noble MEM, Cano C. Miller DC, et al. Among authors: endicott ja. Org Biomol Chem. 2018 Mar 14;16(11):1843-1850. doi: 10.1039/c8ob00099a. Org Biomol Chem. 2018. PMID: 29469144 Free PMC article.

2

The cyclin box fold: protein recognition in cell-cycle and transcription control.

Noble ME, Endicott JA, Brown NR, Johnson LN. Noble ME, et al. Among authors: endicott ja. Trends Biochem Sci. 1997 Dec;22(12):482-7. doi: 10.1016/s0968-0004(97)01144-4. Trends Biochem Sci. 1997. PMID: 9433129 Review.

3

Structural principles in cell-cycle control: beyond the CDKs.

Endicott JA, Noble ME. Endicott JA, et al. Structure. 1998 May 15;6(5):535-41. doi: 10.1016/s0969-2126(98)00055-0. Structure. 1998. PMID: 9634691 Free article. Review.

4

Chemical inhibitors of cyclin-dependent kinases: insights into design from X-ray crystallographic studies.

Noble ME, Endicott JA. Noble ME, et al. Among authors: endicott ja. Pharmacol Ther. 1999 May-Jun;82(2-3):269-78. doi: 10.1016/s0163-7258(98)00051-5. Pharmacol Ther. 1999. PMID: 10454204 Review.

5

The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases.

Brown NR, Noble ME, Endicott JA, Johnson LN. Brown NR, et al. Among authors: endicott ja. Nat Cell Biol. 1999 Nov;1(7):438-43. doi: 10.1038/15674. Nat Cell Biol. 1999. PMID: 10559988

6

Cyclin-dependent kinases: inhibition and substrate recognition.

Endicott JA, Noble ME, Tucker JA. Endicott JA, et al. Curr Opin Struct Biol. 1999 Dec;9(6):738-44. doi: 10.1016/s0959-440x(99)00038-x. Curr Opin Struct Biol. 1999. PMID: 10607671 Review.

7

Identification of novel purine and pyrimidine cyclin-dependent kinase inhibitors with distinct molecular interactions and tumor cell growth inhibition profiles.

Arris CE, Boyle FT, Calvert AH, Curtin NJ, Endicott JA, Garman EF, Gibson AE, Golding BT, Grant S, Griffin RJ, Jewsbury P, Johnson LN, Lawrie AM, Newell DR, Noble ME, Sausville EA, Schultz R, Yu W. Arris CE, et al. Among authors: endicott ja. J Med Chem. 2000 Jul 27;43(15):2797-804. doi: 10.1021/jm990628o. J Med Chem. 2000. PMID: 10956187

8

Probing the ATP ribose-binding domain of cyclin-dependent kinases 1 and 2 with O(6)-substituted guanine derivatives.

Gibson AE, Arris CE, Bentley J, Boyle FT, Curtin NJ, Davies TG, Endicott JA, Golding BT, Grant S, Griffin RJ, Jewsbury P, Johnson LN, Mesguiche V, Newell DR, Noble ME, Tucker JA, Whitfield HJ. Gibson AE, et al. Among authors: endicott ja. J Med Chem. 2002 Aug 1;45(16):3381-93. doi: 10.1021/jm020056z. J Med Chem. 2002. PMID: 12139449

9

Structural studies with inhibitors of the cell cycle regulatory kinase cyclin-dependent protein kinase 2.

Johnson LN, De Moliner E, Brown NR, Song H, Barford D, Endicott JA, Noble ME. Johnson LN, et al. Among authors: endicott ja. Pharmacol Ther. 2002 Feb-Mar;93(2-3):113-24. doi: 10.1016/s0163-7258(02)00181-x. Pharmacol Ther. 2002. PMID: 12191604 Review.

10

Structure-based design of cyclin-dependent kinase inhibitors.

Davies TG, Pratt DJ, Endicott JA, Johnson LN, Noble ME. Davies TG, et al. Among authors: endicott ja. Pharmacol Ther. 2002 Feb-Mar;93(2-3):125-33. doi: 10.1016/s0163-7258(02)00182-1. Pharmacol Ther. 2002. PMID: 12191605 Review.

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