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Page 1
Altered regulation and expression of genes by BET family of proteins in COPD patients.
Malhotra R, Kurian N, Zhou XH, Jiang F, Monkley S, DeMicco A, Clausen IG, Dellgren G, Edenro G, Ahdesmäki MJ, Clausen M, Öberg L, Israelsson E, Belfield G, Vaarala O. Malhotra R, et al. Among authors: vaarala o. PLoS One. 2017 Mar 1;12(3):e0173115. doi: 10.1371/journal.pone.0173115. eCollection 2017. PLoS One. 2017. PMID: 28248992 Free PMC article.
Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation.
Jevnikar Z, Östling J, Ax E, Calvén J, Thörn K, Israelsson E, Öberg L, Singhania A, Lau LCK, Wilson SJ, Ward JA, Chauhan A, Sousa AR, De Meulder B, Loza MJ, Baribaud F, Sterk PJ, Chung KF, Sun K, Guo Y, Adcock IM, Payne D, Dahlen B, Chanez P, Shaw DE, Krug N, Hohlfeld JM, Sandström T, Djukanovic R, James A, Hinks TSC, Howarth PH, Vaarala O, van Geest M, Olsson H; Unbiased Biomarkers in Prediction of Respiratory Disease Outcomes study group. Jevnikar Z, et al. Among authors: vaarala o. J Allergy Clin Immunol. 2019 Feb;143(2):577-590. doi: 10.1016/j.jaci.2018.05.026. Epub 2018 Jun 11. J Allergy Clin Immunol. 2019. PMID: 29902480 Free article.
Dual Role For A MEK Inhibitor As A Modulator Of Inflammation And Host Defense Mechanisms With Potential Therapeutic Application In COPD.
Kurian N, Cohen TS, Öberg L, De Zan E, Skogberg G, Vollmer S, Baturcam E, Svanberg P, Bonn B, Smith PD, Vaarala O, Cunoosamy DM. Kurian N, et al. Among authors: vaarala o. Int J Chron Obstruct Pulmon Dis. 2019 Nov 26;14:2611-2624. doi: 10.2147/COPD.S211619. eCollection 2019. Int J Chron Obstruct Pulmon Dis. 2019. PMID: 32063702 Free PMC article.
A MALT1 inhibitor suppresses human myeloid DC, effector T-cell and B-cell responses and retains Th1/regulatory T-cell homeostasis.
Dumont C, Sivars U, Andreasson T, Odqvist L, Mattsson J, DeMicco A, Pardali K, Johansson G, Yrlid L, Cox RJ, Seeliger F, Larsson M, Gehrmann U, Davis AM, Vaarala O. Dumont C, et al. Among authors: vaarala o. PLoS One. 2020 Sep 1;15(9):e0222548. doi: 10.1371/journal.pone.0222548. eCollection 2020. PLoS One. 2020. PMID: 32870913 Free PMC article.
Genetic variations in A20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus.
Odqvist L, Jevnikar Z, Riise R, Öberg L, Rhedin M, Leonard D, Yrlid L, Jackson S, Mattsson J, Nanda S, Cohen P, Knebel A, Arthur S, Thörn K, Svenungsson E, Jönsen A, Gunnarsson I, Tandre K, Alexsson A, Kastbom A, Rantapää-Dahlqvist S, Eloranta ML, Syvänen AC, Bengtsson A, Johansson P, Sandling JK, Sjöwall C, Rönnblom L, Collins B, Vaarala O. Odqvist L, et al. Among authors: vaarala o. Ann Rheum Dis. 2019 Oct;78(10):1363-1370. doi: 10.1136/annrheumdis-2019-215434. Epub 2019 Jul 12. Ann Rheum Dis. 2019. PMID: 31300459 Free PMC article.
Lanosterol Synthase Regulates Human Rhinovirus Replication in Human Bronchial Epithelial Cells.
McCrae C, Dzgoev A, Ståhlman M, Horndahl J, Svärd R, Große A, Großkopf T, Skujat MA, Williams N, Schubert S, Echeverri C, Jackson C, Guedán A, Solari R, Vaarala O, Kraan M, Rådinger M. McCrae C, et al. Among authors: vaarala o. Am J Respir Cell Mol Biol. 2018 Dec;59(6):713-722. doi: 10.1165/rcmb.2017-0438OC. Am J Respir Cell Mol Biol. 2018. PMID: 30084659
IL-17-high asthma with features of a psoriasis immunophenotype.
Östling J, van Geest M, Schofield JPR, Jevnikar Z, Wilson S, Ward J, Lutter R, Shaw DE, Bakke PS, Caruso M, Dahlen SE, Fowler SJ, Horváth I, Krug N, Montuschi P, Sanak M, Sandström T, Sun K, Pandis I, Auffray C, Sousa AR, Guo Y, Adcock IM, Howarth P, Chung KF, Bigler J, Sterk PJ, Skipp PJ, Djukanović R, Vaarala O; U-BIOPRED Study Group. Östling J, et al. Among authors: vaarala o. J Allergy Clin Immunol. 2019 Nov;144(5):1198-1213. doi: 10.1016/j.jaci.2019.03.027. Epub 2019 Apr 15. J Allergy Clin Immunol. 2019. PMID: 30998987 Free article. Clinical Trial.
276 results