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Identifying Medical Diagnoses and Treatable Diseases by Image-Based Deep Learning.
Kermany DS, Goldbaum M, Cai W, Valentim CCS, Liang H, Baxter SL, McKeown A, Yang G, Wu X, Yan F, Dong J, Prasadha MK, Pei J, Ting MYL, Zhu J, Li C, Hewett S, Dong J, Ziyar I, Shi A, Zhang R, Zheng L, Hou R, Shi W, Fu X, Duan Y, Huu VAN, Wen C, Zhang ED, Zhang CL, Li O, Wang X, Singer MA, Sun X, Xu J, Tafreshi A, Lewis MA, Xia H, Zhang K. Kermany DS, et al. Among authors: wen c. Cell. 2018 Feb 22;172(5):1122-1131.e9. doi: 10.1016/j.cell.2018.02.010. Cell. 2018. PMID: 29474911 Free article.
Evaluation and accurate diagnoses of pediatric diseases using artificial intelligence.
Liang H, Tsui BY, Ni H, Valentim CCS, Baxter SL, Liu G, Cai W, Kermany DS, Sun X, Chen J, He L, Zhu J, Tian P, Shao H, Zheng L, Hou R, Hewett S, Li G, Liang P, Zang X, Zhang Z, Pan L, Cai H, Ling R, Li S, Cui Y, Tang S, Ye H, Huang X, He W, Liang W, Zhang Q, Jiang J, Yu W, Gao J, Ou W, Deng Y, Hou Q, Wang B, Yao C, Liang Y, Zhang S, Duan Y, Zhang R, Gibson S, Zhang CL, Li O, Zhang ED, Karin G, Nguyen N, Wu X, Wen C, Xu J, Xu W, Wang B, Wang W, Li J, Pizzato B, Bao C, Xiang D, He W, He S, Zhou Y, Haw W, Goldbaum M, Tremoulet A, Hsu CN, Carter H, Zhu L, Zhang K, Xia H. Liang H, et al. Among authors: wen c. Nat Med. 2019 Mar;25(3):433-438. doi: 10.1038/s41591-018-0335-9. Epub 2019 Feb 11. Nat Med. 2019. PMID: 30742121
P16INK4a Upregulation Mediated by SIX6 Defines Retinal Ganglion Cell Pathogenesis in Glaucoma.
Skowronska-Krawczyk D, Zhao L, Zhu J, Weinreb RN, Cao G, Luo J, Flagg K, Patel S, Wen C, Krupa M, Luo H, Ouyang H, Lin D, Wang W, Li G, Xu Y, Li O, Chung C, Yeh E, Jafari M, Ai M, Zhong Z, Shi W, Zheng L, Krawczyk M, Chen D, Shi C, Zin C, Zhu J, Mellon PL, Gao W, Abagyan R, Zhang L, Sun X, Zhong S, Zhuo Y, Rosenfeld MG, Liu Y, Zhang K. Skowronska-Krawczyk D, et al. Among authors: wen c. Mol Cell. 2015 Sep 17;59(6):931-40. doi: 10.1016/j.molcel.2015.07.027. Epub 2015 Sep 10. Mol Cell. 2015. PMID: 26365380 Free PMC article.
Genetic and environmental factors strongly influence risk, severity and progression of age-related macular degeneration.
Wang W, Gawlik K, Lopez J, Wen C, Zhu J, Wu F, Shi W, Scheibler S, Cai H, Vairavan R, Shi A, Haw W, Ferreyra H, Zhang M, Chang S, Zhang K. Wang W, et al. Among authors: wen c. Signal Transduct Target Ther. 2016 Sep 16;1:16016. doi: 10.1038/sigtrans.2016.16. eCollection 2016. Signal Transduct Target Ther. 2016. PMID: 29263899 Free PMC article.
Lens regeneration using endogenous stem cells with gain of visual function.
Lin H, Ouyang H, Zhu J, Huang S, Liu Z, Chen S, Cao G, Li G, Signer RA, Xu Y, Chung C, Zhang Y, Lin D, Patel S, Wu F, Cai H, Hou J, Wen C, Jafari M, Liu X, Luo L, Zhu J, Qiu A, Hou R, Chen B, Chen J, Granet D, Heichel C, Shang F, Li X, Krawczyk M, Skowronska-Krawczyk D, Wang Y, Shi W, Chen D, Zhong Z, Zhong S, Zhang L, Chen S, Morrison SJ, Maas RL, Zhang K, Liu Y. Lin H, et al. Among authors: wen c. Nature. 2016 Mar 17;531(7594):323-8. doi: 10.1038/nature17181. Epub 2016 Mar 9. Nature. 2016. PMID: 26958831 Free PMC article.
Nanoparticle biointerfacing by platelet membrane cloaking.
Hu CM, Fang RH, Wang KC, Luk BT, Thamphiwatana S, Dehaini D, Nguyen P, Angsantikul P, Wen CH, Kroll AV, Carpenter C, Ramesh M, Qu V, Patel SH, Zhu J, Shi W, Hofman FM, Chen TC, Gao W, Zhang K, Chien S, Zhang L. Hu CM, et al. Among authors: wen ch. Nature. 2015 Oct 1;526(7571):118-21. doi: 10.1038/nature15373. Epub 2015 Sep 16. Nature. 2015. PMID: 26374997 Free PMC article.
Lanosterol reverses protein aggregation in cataracts.
Zhao L, Chen XJ, Zhu J, Xi YB, Yang X, Hu LD, Ouyang H, Patel SH, Jin X, Lin D, Wu F, Flagg K, Cai H, Li G, Cao G, Lin Y, Chen D, Wen C, Chung C, Wang Y, Qiu A, Yeh E, Wang W, Hu X, Grob S, Abagyan R, Su Z, Tjondro HC, Zhao XJ, Luo H, Hou R, Jefferson J, Perry P, Gao W, Kozak I, Granet D, Li Y, Sun X, Wang J, Zhang L, Liu Y, Yan YB, Zhang K. Zhao L, et al. Among authors: wen c. Nature. 2015 Jul 30;523(7562):607-11. doi: 10.1038/nature14650. Epub 2015 Jul 22. Nature. 2015. PMID: 26200341
Human retinal progenitor cell transplantation preserves vision.
Luo J, Baranov P, Patel S, Ouyang H, Quach J, Wu F, Qiu A, Luo H, Hicks C, Zeng J, Zhu J, Lu J, Sfeir N, Wen C, Zhang M, Reade V, Patel S, Sinden J, Sun X, Shaw P, Young M, Zhang K. Luo J, et al. Among authors: wen c. J Biol Chem. 2014 Mar 7;289(10):6362-6371. doi: 10.1074/jbc.M113.513713. Epub 2014 Jan 9. J Biol Chem. 2014. PMID: 24407289 Free PMC article.
Next generation sequencing-based molecular diagnosis of retinitis pigmentosa: identification of a novel genotype-phenotype correlation and clinical refinements.
Wang F, Wang H, Tuan HF, Nguyen DH, Sun V, Keser V, Bowne SJ, Sullivan LS, Luo H, Zhao L, Wang X, Zaneveld JE, Salvo JS, Siddiqui S, Mao L, Wheaton DK, Birch DG, Branham KE, Heckenlively JR, Wen C, Flagg K, Ferreyra H, Pei J, Khan A, Ren H, Wang K, Lopez I, Qamar R, Zenteno JC, Ayala-Ramirez R, Buentello-Volante B, Fu Q, Simpson DA, Li Y, Sui R, Silvestri G, Daiger SP, Koenekoop RK, Zhang K, Chen R. Wang F, et al. Among authors: wen c. Hum Genet. 2014 Mar;133(3):331-45. doi: 10.1007/s00439-013-1381-5. Epub 2013 Oct 24. Hum Genet. 2014. PMID: 24154662 Free PMC article.
3,927 results