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The monoamine stabilizer (-)-OSU6162 prevents the alcohol deprivation effect and improves motor impulsive behavior in rats.
Addict Biol. 2019 May;24(3):471-484. doi: 10.1111/adb.12613. Epub 2018 Feb 26.
Addict Biol. 2019.
PMID: 29480646
Free PMC article.
Evaluation of guanfacine as a potential medication for alcohol use disorder in long-term drinking rats: behavioral and electrophysiological findings.
Fredriksson I, Jayaram-Lindström N, Wirf M, Nylander E, Nyström E, Jardemark K, Steensland P.
Fredriksson I, et al. Among authors: wirf m.
Neuropsychopharmacology. 2015 Mar 13;40(5):1130-40. doi: 10.1038/npp.2014.294.
Neuropsychopharmacology. 2015.
PMID: 25359257
Free PMC article.
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The monoamine stabilizer (-)-OSU6162 counteracts downregulated dopamine output in the nucleus accumbens of long-term drinking Wistar rats.
Feltmann K, Fredriksson I, Wirf M, Schilström B, Steensland P.
Feltmann K, et al. Among authors: wirf m.
Addict Biol. 2016 Mar;21(2):438-49. doi: 10.1111/adb.12304. Epub 2015 Oct 14.
Addict Biol. 2016.
PMID: 26464265
Free PMC article.
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The monoamine stabilizer OSU6162 has anxiolytic-like properties and reduces voluntary alcohol intake in a genetic rat model of depression.
Melas PA, Wirf M, André H, Jayaram-Lindström N, Mathé AA, Steensland P.
Melas PA, et al. Among authors: wirf m.
Sci Rep. 2021 Jun 4;11(1):11856. doi: 10.1038/s41598-021-91215-1.
Sci Rep. 2021.
PMID: 34088937
Free PMC article.
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