Han W - Search Results

1

Pyridazine and pyridazinone derivatives as potent and selective factor XIa inhibitors.

Hu Z, Wang C, Han W, Rossi KA, Bozarth JM, Wu Y, Sheriff S, Myers JE Jr, Luettgen JM, Seiffert DA, Wexler RR, Quan ML. Hu Z, et al. Among authors: han w. Bioorg Med Chem Lett. 2018 Apr 1;28(6):987-992. doi: 10.1016/j.bmcl.2018.02.049. Epub 2018 Feb 27. Bioorg Med Chem Lett. 2018. PMID: 29501396

2

Synthesis, biological profile, and quantitative structure-activity relationship of a series of novel 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors.

Sit SY, Parker RA, Motoc I, Han W, Balasubramanian N, Catt JD, Brown PJ, Harte WE, Thompson MD, Wright JJ. Sit SY, et al. Among authors: han w. J Med Chem. 1990 Nov;33(11):2982-99. doi: 10.1021/jm00173a013. J Med Chem. 1990. PMID: 2231596

3

A potent, tissue-selective, synthetic inhibitor of HMG-CoA reductase.

Balasubramanian N, Brown PJ, Catt JD, Han WT, Parker RA, Sit SY, Wright JJ. Balasubramanian N, et al. Among authors: han wt. J Med Chem. 1989 Sep;32(9):2038-41. doi: 10.1021/jm00129a004. J Med Chem. 1989. PMID: 2769677 No abstract available.

4

Azetidin-2-one derivatives as inhibitors of thrombin.

Han WT, Trehan AK, Wright JJ, Federici ME, Seiler SM, Meanwell NA. Han WT, et al. Bioorg Med Chem. 1995 Aug;3(8):1123-43. doi: 10.1016/0968-0896(95)00101-l. Bioorg Med Chem. 1995. PMID: 7582985

5

Active site-directed thrombin inhibitors--II. Studies related to arginine/guanidine bioisosteres.

St Laurent DR, Balasubramanian N, Han WT, Trehan A, Federici ME, Meanwell NA, Wright JJ, Seiler SM. St Laurent DR, et al. Among authors: han wt. Bioorg Med Chem. 1995 Aug;3(8):1145-56. doi: 10.1016/0968-0896(95)00103-n. Bioorg Med Chem. 1995. PMID: 7582986

6

Alpha-ketoamides, alpha-ketoesters and alpha-diketones as HCV NS3 protease inhibitors.

Han W, Hu Z, Jiang X, Decicco CP. Han W, et al. Bioorg Med Chem Lett. 2000 Apr 17;10(8):711-3. doi: 10.1016/s0960-894x(00)00074-3. Bioorg Med Chem Lett. 2000. PMID: 10782670

7

Glycine alpha-ketoamides as HCV NS3 protease inhibitors.

Han W, Hu Z, Jiang X, Wasserman ZR, Decicco CP. Han W, et al. Bioorg Med Chem Lett. 2003 Mar 24;13(6):1111-4. doi: 10.1016/s0960-894x(03)00031-3. Bioorg Med Chem Lett. 2003. PMID: 12643923

8

5-Aryl thiazolidine-2,4-diones as selective PPARgamma agonists.

Koyama H, Boueres JK, Han W, Metzger EJ, Bergman JP, Gratale DF, Miller DJ, Tolman RL, MacNaul KL, Berger JP, Doebber TW, Leung K, Moller DE, Heck JV, Sahoo SP. Koyama H, et al. Among authors: han w. Bioorg Med Chem Lett. 2003 May 19;13(10):1801-4. doi: 10.1016/s0960-894x(03)00257-9. Bioorg Med Chem Lett. 2003. PMID: 12729668

9

Investigation of glycine alpha-ketoamide HCV NS3 protease inhibitors: effect of carboxylic acid isosteres.

Han W, Jiang X, Hu Z, Wasserman ZR, Decicco CP. Han W, et al. Bioorg Med Chem Lett. 2005 Aug 1;15(15):3487-90. doi: 10.1016/j.bmcl.2005.06.003. Bioorg Med Chem Lett. 2005. PMID: 15982872

10

Amino(methyl) pyrrolidines as novel scaffolds for factor Xa inhibitors.

Shi Y, Sitkoff D, Zhang J, Han W, Hu Z, Stein PD, Wang Y, Kennedy LJ, O'Connor SP, Ahmad S, Liu EC, Seiler SM, Lam PY, Robl JA, Macor JE, Atwal KS, Zahler R. Shi Y, et al. Among authors: han w. Bioorg Med Chem Lett. 2007 Nov 1;17(21):5952-8. doi: 10.1016/j.bmcl.2007.07.063. Epub 2007 Aug 21. Bioorg Med Chem Lett. 2007. PMID: 17855089

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