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Probing the Tumor Suppressor Function of BAP1 in CRISPR-Engineered Human Liver Organoids.
Artegiani B, van Voorthuijsen L, Lindeboom RGH, Seinstra D, Heo I, Tapia P, López-Iglesias C, Postrach D, Dayton T, Oka R, Hu H, van Boxtel R, van Es JH, Offerhaus J, Peters PJ, van Rheenen J, Vermeulen M, Clevers H. Artegiani B, et al. Among authors: peters pj. Cell Stem Cell. 2019 Jun 6;24(6):927-943.e6. doi: 10.1016/j.stem.2019.04.017. Epub 2019 May 23. Cell Stem Cell. 2019. PMID: 31130514 Free article.
Cryo-EM structures from sub-nl volumes using pin-printing and jet vitrification.
Ravelli RBG, Nijpels FJT, Henderikx RJM, Weissenberger G, Thewessem S, Gijsbers A, Beulen BWAMM, López-Iglesias C, Peters PJ. Ravelli RBG, et al. Among authors: peters pj. Nat Commun. 2020 May 22;11(1):2563. doi: 10.1038/s41467-020-16392-5. Nat Commun. 2020. PMID: 32444637 Free PMC article.
Optimized human intestinal organoid model reveals interleukin-22-dependency of paneth cell formation.
He GW, Lin L, DeMartino J, Zheng X, Staliarova N, Dayton T, Begthel H, van de Wetering WJ, Bodewes E, van Zon J, Tans S, Lopez-Iglesias C, Peters PJ, Wu W, Kotlarz D, Klein C, Margaritis T, Holstege F, Clevers H. He GW, et al. Among authors: peters pj. Cell Stem Cell. 2022 Sep 1;29(9):1333-1345.e6. doi: 10.1016/j.stem.2022.08.002. Epub 2022 Aug 23. Cell Stem Cell. 2022. PMID: 36002022 Free PMC article.
Engineered human hepatocyte organoids enable CRISPR-based target discovery and drug screening for steatosis.
Hendriks D, Brouwers JF, Hamer K, Geurts MH, Luciana L, Massalini S, López-Iglesias C, Peters PJ, Rodríguez-Colman MJ, Chuva de Sousa Lopes S, Artegiani B, Clevers H. Hendriks D, et al. Among authors: peters pj. Nat Biotechnol. 2023 Nov;41(11):1567-1581. doi: 10.1038/s41587-023-01680-4. Epub 2023 Feb 23. Nat Biotechnol. 2023. PMID: 36823355 Free PMC article.
Tuft cells act as regenerative stem cells in the human intestine.
Huang L, Bernink JH, Giladi A, Krueger D, van Son GJF, Geurts MH, Busslinger G, Lin L, Begthel H, Zandvliet M, Buskens CJ, Bemelman WA, López-Iglesias C, Peters PJ, Clevers H. Huang L, et al. Among authors: peters pj. Nature. 2024 Oct;634(8035):929-935. doi: 10.1038/s41586-024-07952-6. Epub 2024 Oct 2. Nature. 2024. PMID: 39358509 Free PMC article.
283 results