Bieri G - Search Results

1

CRISPR-Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicity.

Kramer NJ, Haney MS, Morgens DW, Jovičić A, Couthouis J, Li A, Ousey J, Ma R, Bieri G, Tsui CK, Shi Y, Hertz NT, Tessier-Lavigne M, Ichida JK, Bassik MC, Gitler AD. Kramer NJ, et al. Among authors: bieri g. Nat Genet. 2018 Apr;50(4):603-612. doi: 10.1038/s41588-018-0070-7. Epub 2018 Mar 5. Nat Genet. 2018. PMID: 29507424 Free PMC article.

2

Profilin 1 associates with stress granules and ALS-linked mutations alter stress granule dynamics.

Figley MD, Bieri G, Kolaitis RM, Taylor JP, Gitler AD. Figley MD, et al. Among authors: bieri g. J Neurosci. 2014 Jun 11;34(24):8083-97. doi: 10.1523/JNEUROSCI.0543-14.2014. J Neurosci. 2014. PMID: 24920614 Free PMC article.

3

Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS.

Jovičić A, Mertens J, Boeynaems S, Bogaert E, Chai N, Yamada SB, Paul JW 3rd, Sun S, Herdy JR, Bieri G, Kramer NJ, Gage FH, Van Den Bosch L, Robberecht W, Gitler AD. Jovičić A, et al. Among authors: bieri g. Nat Neurosci. 2015 Sep;18(9):1226-9. doi: 10.1038/nn.4085. Nat Neurosci. 2015. PMID: 26308983 Free PMC article.

4

Axonal transport and secretion of fibrillar forms of α-synuclein, Aβ42 peptide and HTTExon 1.

Brahic M, Bousset L, Bieri G, Melki R, Gitler AD. Brahic M, et al. Among authors: bieri g. Acta Neuropathol. 2016 Apr;131(4):539-48. doi: 10.1007/s00401-016-1538-0. Epub 2016 Jan 28. Acta Neuropathol. 2016. PMID: 26820848 Free PMC article.

5

Internalization, axonal transport and release of fibrillar forms of alpha-synuclein.

Bieri G, Gitler AD, Brahic M. Bieri G, et al. Neurobiol Dis. 2018 Jan;109(Pt B):219-225. doi: 10.1016/j.nbd.2017.03.007. Epub 2017 Mar 16. Neurobiol Dis. 2018. PMID: 28323023 Free PMC article. Review.

6

Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice.

Becker LA, Huang B, Bieri G, Ma R, Knowles DA, Jafar-Nejad P, Messing J, Kim HJ, Soriano A, Auburger G, Pulst SM, Taylor JP, Rigo F, Gitler AD. Becker LA, et al. Among authors: bieri g. Nature. 2017 Apr 20;544(7650):367-371. doi: 10.1038/nature22038. Epub 2017 Apr 12. Nature. 2017. PMID: 28405022 Free PMC article.

7

LRRK2 modifies α-syn pathology and spread in mouse models and human neurons.

Bieri G, Brahic M, Bousset L, Couthouis J, Kramer NJ, Ma R, Nakayama L, Monbureau M, Defensor E, Schüle B, Shamloo M, Melki R, Gitler AD. Bieri G, et al. Acta Neuropathol. 2019 Jun;137(6):961-980. doi: 10.1007/s00401-019-01995-0. Epub 2019 Mar 29. Acta Neuropathol. 2019. PMID: 30927072 Free PMC article.

8

Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.

White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA. White CW 3rd, et al. Among authors: bieri g. Proc Natl Acad Sci U S A. 2020 Sep 8;117(36):22214-22224. doi: 10.1073/pnas.2007439117. Epub 2020 Aug 26. Proc Natl Acad Sci U S A. 2020. PMID: 32848054 Free PMC article.

9

Loss of neuronal Tet2 enhances hippocampal-dependent cognitive function.

Pratt KJB, Shea JM, Remesal-Gomez L, Bieri G, Smith LK, Couthouis J, Chen CP, Roy IJ, Gontier G, Villeda SA. Pratt KJB, et al. Among authors: bieri g. Cell Rep. 2022 Nov 8;41(6):111612. doi: 10.1016/j.celrep.2022.111612. Cell Rep. 2022. PMID: 36351399 Free PMC article.

10

Mesoscale connections and gene expression empower whole-brain modeling of α-synuclein spread, aggregation, and decay dynamics.

Dadgar-Kiani E, Bieri G, Melki R, Gitler AD, Lee JH. Dadgar-Kiani E, et al. Among authors: bieri g. Cell Rep. 2022 Nov 8;41(6):111631. doi: 10.1016/j.celrep.2022.111631. Cell Rep. 2022. PMID: 36351406 Free PMC article.

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