Tessier-Lavigne M - Search Results

1

CRISPR-Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicity.

Kramer NJ, Haney MS, Morgens DW, Jovičić A, Couthouis J, Li A, Ousey J, Ma R, Bieri G, Tsui CK, Shi Y, Hertz NT, Tessier-Lavigne M, Ichida JK, Bassik MC, Gitler AD. Kramer NJ, et al. Nat Genet. 2018 Apr;50(4):603-612. doi: 10.1038/s41588-018-0070-7. Epub 2018 Mar 5. Nat Genet. 2018. PMID: 29507424 Free PMC article.

2

p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR).

Maor-Nof M, Shipony Z, Lopez-Gonzalez R, Nakayama L, Zhang YJ, Couthouis J, Blum JA, Castruita PA, Linares GR, Ruan K, Ramaswami G, Simon DJ, Nof A, Santana M, Han K, Sinnott-Armstrong N, Bassik MC, Geschwind DH, Tessier-Lavigne M, Attardi LD, Lloyd TE, Ichida JK, Gao FB, Greenleaf WJ, Yokoyama JS, Petrucelli L, Gitler AD. Maor-Nof M, et al. Cell. 2021 Feb 4;184(3):689-708.e20. doi: 10.1016/j.cell.2020.12.025. Epub 2021 Jan 21. Cell. 2021. PMID: 33482083 Free PMC article.

3

Neuronally Enriched RUFY3 Is Required for Caspase-Mediated Axon Degeneration.

Hertz NT, Adams EL, Weber RA, Shen RJ, O'Rourke MK, Simon DJ, Zebroski H, Olsen O, Morgan CW, Mileur TR, Hitchcock AM, Sinnott Armstrong NA, Wainberg M, Bassik MC, Molina H, Wells JA, Tessier-Lavigne M. Hertz NT, et al. Neuron. 2019 Aug 7;103(3):412-422.e4. doi: 10.1016/j.neuron.2019.05.030. Epub 2019 Jun 17. Neuron. 2019. PMID: 31221560 Free PMC article.

4

Structural plasticity of actin-spectrin membrane skeleton and functional role of actin and spectrin in axon degeneration.

Wang G, Simon DJ, Wu Z, Belsky DM, Heller E, O'Rourke MK, Hertz NT, Molina H, Zhong G, Tessier-Lavigne M, Zhuang X. Wang G, et al. Elife. 2019 May 1;8:e38730. doi: 10.7554/eLife.38730. Elife. 2019. PMID: 31042147 Free PMC article.

5

Efficient introduction of specific homozygous and heterozygous mutations using CRISPR/Cas9.

Paquet D, Kwart D, Chen A, Sproul A, Jacob S, Teo S, Olsen KM, Gregg A, Noggle S, Tessier-Lavigne M. Paquet D, et al. Nature. 2016 May 5;533(7601):125-9. doi: 10.1038/nature17664. Epub 2016 Apr 27. Nature. 2016. PMID: 27120160

6

Functional analysis of secreted and transmembrane proteins critical to mouse development.

Mitchell KJ, Pinson KI, Kelly OG, Brennan J, Zupicich J, Scherz P, Leighton PA, Goodrich LV, Lu X, Avery BJ, Tate P, Dill K, Pangilinan E, Wakenight P, Tessier-Lavigne M, Skarnes WC. Mitchell KJ, et al. Nat Genet. 2001 Jul;28(3):241-9. doi: 10.1038/90074. Nat Genet. 2001. PMID: 11431694

7

Axon Degeneration Gated by Retrograde Activation of Somatic Pro-apoptotic Signaling.

Simon DJ, Pitts J, Hertz NT, Yang J, Yamagishi Y, Olsen O, Tešić Mark M, Molina H, Tessier-Lavigne M. Simon DJ, et al. Cell. 2016 Feb 25;164(5):1031-45. doi: 10.1016/j.cell.2016.01.032. Epub 2016 Feb 18. Cell. 2016. PMID: 26898330 Free PMC article.

8

APP binds DR6 to trigger axon pruning and neuron death via distinct caspases.

Nikolaev A, McLaughlin T, O'Leary DD, Tessier-Lavigne M. Nikolaev A, et al. Nature. 2009 Feb 19;457(7232):981-9. doi: 10.1038/nature07767. Nature. 2009. Retraction in: Nature. 2024 Jan;625(7993):204. doi: 10.1038/s41586-023-06943-3 PMID: 19225519 Free PMC article. Retracted.

9

Boc is a receptor for sonic hedgehog in the guidance of commissural axons.

Okada A, Charron F, Morin S, Shin DS, Wong K, Fabre PJ, Tessier-Lavigne M, McConnell SK. Okada A, et al. Nature. 2006 Nov 16;444(7117):369-73. doi: 10.1038/nature05246. Epub 2006 Nov 1. Nature. 2006. PMID: 17086203

10

Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptors.

Leonardo ED, Hinck L, Masu M, Keino-Masu K, Ackerman SL, Tessier-Lavigne M. Leonardo ED, et al. Nature. 1997 Apr 24;386(6627):833-8. doi: 10.1038/386833a0. Nature. 1997. PMID: 9126742

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