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A Restricted Role for FcγR in the Regulation of Adaptive Immunity.
Fransen MF, Benonisson H, van Maren WW, Sow HS, Breukel C, Linssen MM, Claassens JWC, Brouwers C, van der Kaa J, Camps M, Kleinovink JW, Vonk KK, van Heiningen S, Klar N, van Beek L, van Harmelen V, Daxinger L, Nandakumar KS, Holmdahl R, Coward C, Lin Q, Hirose S, Salvatori D, van Hall T, van Kooten C, Mastroeni P, Ossendorp F, Verbeek JS. Fransen MF, et al. Among authors: linssen mm. J Immunol. 2018 Apr 15;200(8):2615-2626. doi: 10.4049/jimmunol.1700429. Epub 2018 Mar 9. J Immunol. 2018. PMID: 29523656 Free PMC article.
SCON-a Short Conditional intrON for conditional knockout with one-step zygote injection.
Wu SS, Lee H, Szép-Bakonyi R, Colozza G, Boese A, Gert KR, Hallay N, Lee JH, Kim J, Zhu Y, Linssen MM, Pilat-Carotta S, Hohenstein P, Theussl HC, Pauli A, Koo BK. Wu SS, et al. Among authors: linssen mm. Exp Mol Med. 2022 Dec;54(12):2188-2199. doi: 10.1038/s12276-022-00891-0. Epub 2022 Dec 9. Exp Mol Med. 2022. PMID: 36494589 Free PMC article.
A dystrophic Duchenne mouse model for testing human antisense oligonucleotides.
Veltrop M, van Vliet L, Hulsker M, Claassens J, Brouwers C, Breukel C, van der Kaa J, Linssen MM, den Dunnen JT, Verbeek S, Aartsma-Rus A, van Putten M. Veltrop M, et al. Among authors: linssen mm. PLoS One. 2018 Feb 21;13(2):e0193289. doi: 10.1371/journal.pone.0193289. eCollection 2018. PLoS One. 2018. PMID: 29466448 Free PMC article.
FcγRI expression on macrophages is required for antibody-mediated tumor protection by cytomegalovirus-based vaccines.
Benonisson H, Sow HS, Breukel C, Claassens JWC, Brouwers C, Linssen MM, Redeker A, Fransen MF, van Hall T, Ossendorp F, Arens R, Verbeek S. Benonisson H, et al. Among authors: linssen mm. Oncotarget. 2018 Jun 29;9(50):29392-29402. doi: 10.18632/oncotarget.25630. eCollection 2018 Jun 29. Oncotarget. 2018. PMID: 30034625 Free PMC article.
FcγR interaction is not required for effective anti-PD-L1 immunotherapy but can add additional benefit depending on the tumor model.
Sow HS, Benonisson H, Breukel C, Visser R, Verhagen OJHM, Bentlage AEH, Brouwers C, Claassens JWC, Linssen MM, Camps M, van Hall T, Ossendorp F, Fransen MF, Vidarsson G, Verbeek JS. Sow HS, et al. Among authors: linssen mm. Int J Cancer. 2019 Jan 15;144(2):345-354. doi: 10.1002/ijc.31899. Epub 2018 Nov 12. Int J Cancer. 2019. PMID: 30259976
First FHM3 mouse model shows spontaneous cortical spreading depolarizations.
Jansen NA, Dehghani A, Linssen MML, Breukel C, Tolner EA, van den Maagdenberg AMJM. Jansen NA, et al. Among authors: linssen mml. Ann Clin Transl Neurol. 2020 Jan;7(1):132-138. doi: 10.1002/acn3.50971. Epub 2019 Dec 27. Ann Clin Transl Neurol. 2020. PMID: 31880072 Free PMC article.
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