Zhao D - Search Results

1

Covalently mucoadhesive amphiphilic prodrug of 5-fluorouracil for enhanced permeation and improved oral absorption.

Liu Y, Zhao D, Sun M, Wei W, Wang Y, Zhou J, Zhang R, Wang J, Zhang H, He Z, Kan Q, Sun J. Liu Y, et al. Among authors: zhao d. Drug Deliv Transl Res. 2018 Jun;8(3):645-656. doi: 10.1007/s13346-018-0502-z. Drug Deliv Transl Res. 2018. PMID: 29532356

2

Enzymatic activation of double-targeted 5'-O-L-valyl-decitabine prodrug by biphenyl hydrolase-like protein and its molecular design basis.

Tao W, Zhao D, Sun M, Li M, Zhang X, He Z, Sun Y, Sun J. Tao W, et al. Among authors: zhao d. Drug Deliv Transl Res. 2017 Apr;7(2):304-311. doi: 10.1007/s13346-016-0356-1. Drug Deliv Transl Res. 2017. PMID: 28070705

3

A rapid albumin-binding 5-fluorouracil prodrug with a prolonged circulation time and enhanced antitumor activity.

Zhao D, Zhang H, Tao W, Wei W, Sun J, He Z. Zhao D, et al. Biomater Sci. 2017 Feb 28;5(3):502-510. doi: 10.1039/c6bm00884d. Biomater Sci. 2017. PMID: 28116362

4

A novel oral prodrug-targeting transporter MCT 1: 5-fluorouracil-dicarboxylate monoester conjugates.

Sun Y, Zhao D, Wang G, Jiang Q, Guo M, Kan Q, He Z, Sun J. Sun Y, et al. Among authors: zhao d. Asian J Pharm Sci. 2019 Nov;14(6):631-639. doi: 10.1016/j.ajps.2019.04.001. Epub 2019 Apr 25. Asian J Pharm Sci. 2019. PMID: 32104489 Free PMC article.

5

Polydopamine-modified ROS-responsive prodrug nanoplatform with enhanced stability for precise treatment of breast cancer.

Yang B, Wang K, Zhang D, Ji B, Zhao D, Wang X, Zhang H, Kan Q, He Z, Sun J. Yang B, et al. Among authors: zhao d. RSC Adv. 2019 Mar 21;9(16):9260-9269. doi: 10.1039/c9ra01230c. eCollection 2019 Mar 15. RSC Adv. 2019. PMID: 35517686 Free PMC article.

6

Combination of l-Carnitine with Lipophilic Linkage-Donating Gemcitabine Derivatives as Intestinal Novel Organic Cation Transporter 2-Targeting Oral Prodrugs.

Wang G, Chen H, Zhao D, Ding D, Sun M, Kou L, Luo C, Zhang D, Yi X, Dong J, Wang J, Liu X, He Z, Sun J. Wang G, et al. Among authors: zhao d. J Med Chem. 2017 Mar 23;60(6):2552-2561. doi: 10.1021/acs.jmedchem.7b00049. Epub 2017 Mar 7. J Med Chem. 2017. PMID: 28234466

7

Intestinal absorption and activation of decitabine amino acid ester prodrugs mediated by peptide transporter PEPT1 and enterocyte enzymes.

Tao W, Zhao D, Sun M, Wang Z, Lin B, Bao Y, Li Y, He Z, Sun Y, Sun J. Tao W, et al. Among authors: zhao d. Int J Pharm. 2018 Apr 25;541(1-2):64-71. doi: 10.1016/j.ijpharm.2018.02.033. Epub 2018 Feb 19. Int J Pharm. 2018. PMID: 29471144

8

Striking a Balance between Carbonate/Carbamate Linkage Bond- and Reduction-Sensitive Disulfide Bond-Bearing Linker for Tailored Controlled Release: In Situ Covalent-Albumin-Binding Gemcitabine Prodrugs Promote Bioavailability and Tumor Accumulation.

Zhang H, Wang K, Na K, Li D, Li Z, Zhao D, Zhong L, Wang M, Kou L, Luo C, Zhang H, Kan Q, Ding H, He Z, Sun J. Zhang H, et al. Among authors: zhao d. J Med Chem. 2018 Jun 14;61(11):4904-4917. doi: 10.1021/acs.jmedchem.8b00293. Epub 2018 May 24. J Med Chem. 2018. PMID: 29768008

9

Precisely albumin-hitchhiking tumor cell-activated reduction/oxidation-responsive docetaxel prodrugs for the hyperselective treatment of breast cancer.

Wei W, Luo C, Yang J, Sun B, Zhao D, Liu Y, Wang Y, Yang W, Kan Q, Sun J, He Z. Wei W, et al. Among authors: zhao d. J Control Release. 2018 Sep 10;285:187-199. doi: 10.1016/j.jconrel.2018.07.010. Epub 2018 Jul 12. J Control Release. 2018. PMID: 30017721

10

Transformative hyaluronic acid-based active targeting supramolecular nanoplatform improves long circulation and enhances cellular uptake in cancer therapy.

Zhong L, Xu L, Liu Y, Li Q, Zhao D, Li Z, Zhang H, Zhang H, Kan Q, Wang Y, Sun J, He Z. Zhong L, et al. Among authors: zhao d. Acta Pharm Sin B. 2019 Mar;9(2):397-409. doi: 10.1016/j.apsb.2018.11.006. Epub 2018 Nov 29. Acta Pharm Sin B. 2019. PMID: 30972285 Free PMC article.

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