Liu YC - Search Results

1

Discovery of potent DOT1L inhibitors by AlphaLISA based High Throughput Screening assay.

Song Y, Li L, Chen Y, Liu J, Xiao S, Lian F, Zhang N, Ding H, Zhang Y, Chen K, Jiang H, Zhang C, Liu YC, Chen S, Luo C. Song Y, et al. Among authors: liu j, liu yc. Bioorg Med Chem. 2018 May 1;26(8):1751-1758. doi: 10.1016/j.bmc.2018.02.020. Epub 2018 Feb 24. Bioorg Med Chem. 2018. PMID: 29534934

2

Identifying novel selective non-nucleoside DNA methyltransferase 1 inhibitors through docking-based virtual screening.

Chen S, Wang Y, Zhou W, Li S, Peng J, Shi Z, Hu J, Liu YC, Ding H, Lin Y, Li L, Cheng S, Liu J, Lu T, Jiang H, Liu B, Zheng M, Luo C. Chen S, et al. Among authors: liu j, liu b, liu yc. J Med Chem. 2014 Nov 13;57(21):9028-41. doi: 10.1021/jm501134e. Epub 2014 Nov 4. J Med Chem. 2014. PMID: 25333769

3

Fragment-based drug discovery of 2-thiazolidinones as BRD4 inhibitors: 2. Structure-based optimization.

Zhao L, Wang Y, Cao D, Chen T, Wang Q, Li Y, Xu Y, Zhang N, Wang X, Chen D, Chen L, Chen YL, Xia G, Shi Z, Liu YC, Lin Y, Miao Z, Shen J, Xiong B. Zhao L, et al. Among authors: liu yc. J Med Chem. 2015 Feb 12;58(3):1281-97. doi: 10.1021/jm501504k. Epub 2015 Jan 14. J Med Chem. 2015. PMID: 25559428

4

Discovery and Optimization of Novel, Selective Histone Methyltransferase SET7 Inhibitors by Pharmacophore- and Docking-Based Virtual Screening.

Meng F, Cheng S, Ding H, Liu S, Liu Y, Zhu K, Chen S, Lu J, Xie Y, Li L, Liu R, Shi Z, Zhou Y, Liu YC, Zheng M, Jiang H, Lu W, Liu H, Luo C. Meng F, et al. Among authors: liu y, liu h, liu s, liu r, liu yc. J Med Chem. 2015 Oct 22;58(20):8166-81. doi: 10.1021/acs.jmedchem.5b01154. Epub 2015 Sep 30. J Med Chem. 2015. PMID: 26390175

5

Design and discovery of new pyrimidine coupled nitrogen aromatic rings as chelating groups of JMJD3 inhibitors.

Hu J, Wang X, Chen L, Huang M, Tang W, Zuo J, Liu YC, Shi Z, Liu R, Shen J, Xiong B. Hu J, et al. Among authors: liu r, liu yc. Bioorg Med Chem Lett. 2016 Feb 1;26(3):721-725. doi: 10.1016/j.bmcl.2016.01.006. Epub 2016 Jan 7. Bioorg Med Chem Lett. 2016. PMID: 26776360

6

Identification of Novel Disruptor of Telomeric Silencing 1-like (DOT1L) Inhibitors through Structure-Based Virtual Screening and Biological Assays.

Chen S, Li L, Chen Y, Hu J, Liu J, Liu YC, Liu R, Zhang Y, Meng F, Zhu K, Lu J, Zheng M, Chen K, Zhang J, Jiang H, Yao Z, Luo C. Chen S, et al. Among authors: liu j, liu r, liu yc. J Chem Inf Model. 2016 Mar 28;56(3):527-34. doi: 10.1021/acs.jcim.5b00738. Epub 2016 Mar 4. J Chem Inf Model. 2016. PMID: 26914852

7

Identification of novel EZH2 inhibitors through pharmacophore-based virtual screening and biological assays.

Wu Y, Hu J, Ding H, Chen L, Zhang Y, Liu R, Xu P, Du D, Lu W, Liu J, Liu Y, Liu YC, Lu J, Zhang J, Yao Z, Luo C. Wu Y, et al. Among authors: liu j, liu y, liu r, liu yc. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3813-7. doi: 10.1016/j.bmcl.2016.05.018. Epub 2016 May 30. Bioorg Med Chem Lett. 2016. PMID: 27289323

8

Discovery of Novel Inhibitors Targeting the Menin-Mixed Lineage Leukemia Interface Using Pharmacophore- and Docking-Based Virtual Screening.

Xu Y, Yue L, Wang Y, Xing J, Chen Z, Shi Z, Liu R, Liu YC, Luo X, Jiang H, Chen K, Luo C, Zheng M. Xu Y, et al. Among authors: liu r, liu yc. J Chem Inf Model. 2016 Sep 26;56(9):1847-55. doi: 10.1021/acs.jcim.6b00185. Epub 2016 Aug 24. J Chem Inf Model. 2016. PMID: 27513308

9

Discovery of novel DNA methyltransferase 3A inhibitors via structure-based virtual screening and biological assays.

Shao Z, Xu P, Xu W, Li L, Liu S, Zhang R, Liu YC, Zhang C, Chen S, Luo C. Shao Z, et al. Among authors: liu s, liu yc. Bioorg Med Chem Lett. 2017 Jan 15;27(2):342-346. doi: 10.1016/j.bmcl.2016.11.023. Epub 2016 Nov 11. Bioorg Med Chem Lett. 2017. PMID: 27899265

10

Marine-derived chromopeptide A, a novel class I HDAC inhibitor, suppresses human prostate cancer cell proliferation and migration.

Sun JY, Wang JD, Wang X, Liu HC, Zhang MM, Liu YC, Zhang CH, Su Y, Shen YY, Guo YW, Shen AJ, Geng MY. Sun JY, et al. Among authors: liu yc, liu hc. Acta Pharmacol Sin. 2017 Apr;38(4):551-560. doi: 10.1038/aps.2016.139. Epub 2017 Jan 23. Acta Pharmacol Sin. 2017. PMID: 28112184 Free PMC article.

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